Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.
about
The retinoid X receptors and their ligandsTRIM5 alpha cytoplasmic bodies are highly dynamic structures.Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.Oncogenic conversion of the thyroid hormone receptor by altered nuclear transport.Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging.Dominant-negative mechanism of leukemogenic PAX5 fusions.Estrogen-related Receptor β Reduces the Subnuclear Mobility of Estrogen Receptor α and Suppresses Estrogen-dependent Cellular Function.Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell levelChaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO.The cell biology of TRIM5α.Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility.The reduced and altered activities of PAX5 are linked to the protein-protein interaction motif (coiled-coil domain) of the PAX5-PML fusion protein in t(9;15)-associated acute lymphocytic leukemia.Physical and functional interaction of Runt-related protein 1 with hypoxia-inducible factor-1alpha.Different subcellular localisations of TRIM22 suggest species-specific function.Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.Evidence of functional interaction between NuMA-RARalpha and RXRalpha in an in vivo model of acute promyelocytic leukemia.Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer.
P2860
Q24562747-B5A3D0A9-AA67-4682-BB19-57AB4D34132DQ30479495-04EDF01B-C1A1-459A-BEE8-6A6079D61080Q33298860-E51414FC-608B-48B6-944F-1D81EB29340BQ34652178-2583B243-ECED-4D7B-BCCF-BE709593279DQ35085914-A3A1B6F0-FF6E-4E13-A965-870C7780AF6BQ35402092-1BC565C6-606A-4092-AF17-23CC59198235Q35583190-616CEA89-D3D0-4F47-B659-2764575C5C1EQ36017077-FAF87EED-7770-431E-8DE7-8B071D987DB2Q36744579-E84F6B81-DDBC-47D3-81C1-994F35EC78B1Q37970939-46E2D393-47F1-4CFA-80F3-AE905B1EA6E4Q39092116-B1F099D6-4ED3-4CF6-846B-CE1E7CE2ED45Q39640399-3C943BE1-ED6A-4AB5-8885-527DD80EC64FQ40096853-815344F3-054D-4D4C-88D0-A1C033FB8577Q41834429-A3A31FED-A21D-48F7-9B39-04A455F4EC95Q42730910-7B56EED0-61CF-490D-98E2-8ADE900B8A86Q42814510-2FFDD140-3EE8-47F3-9058-DB98614F83D4Q45282569-968CB03A-AA60-4230-9023-A203443CD645Q45878864-097066CE-5B2D-4EA1-B9DB-094D528799D1Q46735339-D62C419B-2EAE-4A24-8591-DAF373381B38
P2860
Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@en
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@nl
type
label
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@en
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@nl
prefLabel
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@en
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@nl
P2093
P2860
P1476
Reduced intranuclear mobility ...... of retinoid X receptor alpha.
@en
P2093
David J Tweardy
David L Stenoien
Michael A Mancini
P2860
P304
P356
10.1128/MCB.24.10.4465-4475.2004
P407
P577
2004-05-01T00:00:00Z