The splicing factor U2AF small subunit is functionally conserved between fission yeast and humans.
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Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivoNew insights into the RNA-based mechanism of action of the anticancer drug 5'-fluorouracil in eukaryotic cellsExonic splicing enhancers in fission yeast: functional conservation demonstrates an early evolutionary origin.Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicingRecurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes.Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome ActivationA dominant role for meiosis-specific 3' RNA processing in controlling expression of a fission yeast cyclin geneA conditional role of U2AF in splicing of introns with unconventional polypyrimidine tractsAlternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons.The power of fission: yeast as a tool for understanding complex splicing.Factors affecting splicing strength of yeast genes.U2AF1 mutations alter splice site recognition in hematological malignancies.Genomic mRNA profiling reveals compensatory mechanisms for the requirement of the essential splicing factor U2AF.Genomic functions of U2AF in constitutive and regulated splicing.Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeastA novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.Functions for fission yeast splicing factors SpSlu7 and SpPrp18 in alternative splice-site choice and stress-specific regulated splicing.The cancer-associated U2AF35 470A>G (Q157R) mutation creates an in-frame alternative 5' splice site that impacts splicing regulation in Q157R patients.Molecular characterization and phylogeny of U2AF35 homologs in plants.
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The splicing factor U2AF small subunit is functionally conserved between fission yeast and humans.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The splicing factor U2AF small ...... ween fission yeast and humans.
@en
The splicing factor U2AF small ...... ween fission yeast and humans.
@nl
type
label
The splicing factor U2AF small ...... ween fission yeast and humans.
@en
The splicing factor U2AF small ...... ween fission yeast and humans.
@nl
prefLabel
The splicing factor U2AF small ...... ween fission yeast and humans.
@en
The splicing factor U2AF small ...... ween fission yeast and humans.
@nl
P2860
P1476
The splicing factor U2AF small ...... ween fission yeast and humans.
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Christopher J Webb
Jo Ann Wise
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10.1128/MCB.24.10.4229-4240.2004
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2004-05-01T00:00:00Z