The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
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An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiationp38 MAPK Signaling in Osteoblast DifferentiationDual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinaseContext Sensitive Modeling of Cancer Drug SensitivityGenomic Characterization of Metformin Hepatic ResponseDistinct roles for extracellular signal-regulated kinase 1 (ERK1) and ERK2 in the structure and production of a primate gammaherpesvirusInherited genetic variation and overall survival following follicular lymphoma.microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression.A point mutation in translation initiation factor eIF2B leads to function--and time-specific changes in brain gene expression.Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progressionEGFR-mutated lung cancer: a paradigm of molecular oncology.Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancersEnhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma.A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.The anti-apoptotic and cardioprotective effects of salvianolic acid a on rat cardiomyocytes following ischemia/reperfusion by DUSP-mediated regulation of the ERK1/2/JNK pathwayImbalanced expression of mitogen-activated protein kinase phosphatase-1 and phosphorylated extracellular signal-regulated kinases in lung squamous cell carcinoma.Polymorphisms in the DUSP10 gene are associated with sex-specific colorectal cancer risk in a Han populationGlobal gene expression changes in human urothelial cells exposed to low-level monomethylarsonous acid.Differential expression of FOXA1, DUSP6, and HA117 in colon segments of Hirschsprung's disease.Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens.Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription FactorThe dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanismsSilencing of DUSP6 gene by RNAi-mediation inhibits proliferation and growth in MDA-MB-231 breast cancer cells: an in vitro studyDUSPs, to MAP kinases and beyond.A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells.Layer-specific CREB target gene induction in human neocortical epilepsyAlpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium.Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomesHeparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1.Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma riskraw Functions through JNK signaling and cadherin-based adhesion to regulate Drosophila gonad morphogenesis.Dual-specificity Phosphatase 1 Deficiency Induces Endometrioid Adenocarcinoma Progression via Activation of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase PathwayLinking JNK Activity to the DNA Damage Response.Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver.MKP-1 signaling events are required for early osteoclastogenesis in lineage defined progenitor populations by disrupting RANKL-induced NFATc1 nuclear translocation.Association of Topoisomerase II (TOP2A) and Dual-Specificity Phosphatase 6 (DUSP6) Single Nucleotide Polymorphisms with Radiation Treatment Response and Prognosis of Lung Cancer in Han Chinese.Therapeutic regulation of cardiac fibroblast function: targeting stress-activated protein kinase pathways.Protein tyrosine phosphatases in health and disease.Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases.
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The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 May 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@en
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@nl
type
label
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@en
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@nl
prefLabel
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@en
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@nl
P2093
P2860
P1476
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.
@en
P2093
P2860
P304
P356
10.1152/AJPCELL.00347.2009
P577
2010-05-12T00:00:00Z