Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
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The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Impacts of activation of the mitogen-activated protein kinase pathway in pancreatic cancerThe family-wide structure and function of human dual-specificity protein phosphatasesDistinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreasThe protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesismicroRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression.Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.Characterisation of genome-wide PLZF/RARA target genes.Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.Diagnosis and prognostication of ductal adenocarcinomas of the pancreas based on genome-wide DNA methylation profiling by bacterial artificial chromosome array-based methylated CpG island amplification.Induction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human b cells; relevance to cellular transformation.Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia.Elucidation of the relationship of BNIP3 expression to gemcitabine chemosensitivity and prognosisMolecular mechanisms of pancreatic carcinogenesis.Functional p38 MAPK identified by biomarker profiling of pancreatic cancer restrains growth through JNK inhibition and correlates with improved survival.Tackling EGFR signaling with TACE antagonists: a rational target for metalloprotease inhibitors in cancer.An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells.Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease.Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesisExperimental treatment of pancreatic cancer with two novel histone deacetylase inhibitors.ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis.The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.Molecular pathogenesis of pancreatic cancer and clinical perspectives.Targeting DUSPs in glioblastomas - wielding a double-edged sword?Molecular Pathways: Targeting Protein Tyrosine Phosphatases in Cancer.Increased levels of DUSP6 phosphatase stimulate tumourigenesis in a molecularly distinct melanoma subtype.DUSP16 is an epigenetically regulated determinant of JNK signalling in Burkitt's lymphomaWT1 induction of mitogen-activated protein kinase phosphatase 3 represents a novel mechanism of growth suppression.DUSP6, a tumor suppressor, is involved in differentiation and apoptosis in esophageal squamous cell carcinomaExpression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression.Prognostic value of dual-specificity phosphatase 6 expression in non-small cell lung cancer.Dual-specificity phosphatase 6 (DUSP6): a review of its molecular characteristics and clinical relevance in cancer.
P2860
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P2860
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
description
2005 nî lūn-bûn
@nan
2005 թուականին հրատարակուած գիտական յօդուած
@hyw
2005 թվականին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@ast
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@en
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@nl
type
label
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@ast
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@en
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@nl
prefLabel
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@ast
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@en
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@nl
P2093
P1476
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer
@en
P2093
Makoto Sunamura
Naomi Kanai
Shanhai Xu
P2888
P304
P356
10.1007/S10038-005-0235-Y
P407
P577
2005-04-12T00:00:00Z