Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
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The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki diseaseHidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatmentsDesign of a superior cytokine antagonist for topical ophthalmic useA novel human anti-interleukin-1β neutralizing monoclonal antibody showing in vivo efficacyNlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathyToll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses.Ovarian epithelial-stromal interactions: role of interleukins 1 and 6.Assessment of epicardial adipose tissue thickness and the mean platelet volume in children with familial Mediterranean fever.Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes.The inflammasome: pathways linking psychological stress, depression, and systemic illnessesIncreased expression of the NLRP3 inflammasome components in patients with Behçet's diseaseThe Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases.Latest evidence on gout management: what the clinician needs to knowHigh-mobility group box 1 impairs airway epithelial barrier function through the activation of the RAGE/ERK pathway.Critical role for IL-1β in DNA damage-induced mucositis.Sensing damage by the NLRP3 inflammasome.Cold-induced urticaria with a familial transmission: a case report and review of the literature.Regulatory T cells, mTOR kinase, and metabolic activity.IL-1β biological treatment of familial Mediterranean fever.Neutrophils, IL-1β, and gout: is there a link?The NLRP3 inflammasome in Alzheimer's disease.Novel therapeutics for the treatment of familial Mediterranean fever: from colchicine to biologics.Targeting cholesterol crystal-induced inflammation for the secondary prevention of cardiovascular disease.The role of the inflammasome in cardiovascular diseases.Contribution of neovascularization and intraplaque haemorrhage to atherosclerotic plaque progression and instability.Innate immunity in diabetes and diabetic nephropathy.Inflammasome Activation in Chronic Glomerular Diseases.Interleukin-1 antagonists in the treatment of autoinflammatory syndromes, including cryopyrin-associated periodic syndrome.NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils.The experience of canakinumab in renal amyloidosis secondary to Familial Mediterranean fever.Cytokine Profile in Gout: Inflammation Driven by IL-6 and IL-18?Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout.Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A.Neutrophil extracellular traps regulate IL-1β-mediated inflammation in familial Mediterranean fever.Efficacy of an interleukin-1β receptor antagonist (anakinra) in idiopathic recurrent pericarditis.Efficacy and safety of the interleukin-1 antagonist rilonacept in Schnitzler syndrome: an open-label study.Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret®) in a case of refractory Sweet's syndrome.Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.Exploring the association between interleukin-1β and its interacting proteins in Alzheimer's disease.
P2860
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P2860
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@en
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@nl
type
label
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@en
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@nl
prefLabel
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@en
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@nl
P2093
P1476
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.
@en
P2093
Ioannis Mitroulis
Konstantinos Ritis
Panagiotis Skendros
P304
P356
10.1016/J.EJIM.2010.03.005
P577
2010-03-30T00:00:00Z