Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
about
Yeast: a simple model system to study complex phenomena of aneuploidyAneuploidy and drug resistance in pathogenic fungiThe functional basis of adaptive evolution in chemostatsLoss of primary cilia occurs early in breast cancer development.Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients.Stress alters rates and types of loss of heterozygosity in Candida albicans.Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancerThe fitness consequences of aneuploidy are driven by condition-dependent gene effects.Aneuploidy and chromosomal instability in cancer: a jackpot to chaos.Chromosome mis-segregation and cytokinesis failure in trisomic human cellsAdaptation to High Ethanol Reveals Complex Evolutionary PathwaysDoes stress induce (para)sex? Implications for Candida albicans evolutionMutability and mutational spectrum of chromosome transmission fidelity genesHigh variability of genomic instability and gene expression profiling in different HeLa clones.Polyploid titan cells produce haploid and aneuploid progeny to promote stress adaptationThe three clades of the telomere-associated TLO gene family of Candida albicans have different splicing, localization, and expression features.Chromosomal duplication is a transient evolutionary solution to stress.Stress-induced mutation via DNA breaks in Escherichia coli: a molecular mechanism with implications for evolution and medicine.Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy.Multi-layered cancer chromosomal instability phenotype.Temporal and spatial evolution of somatic chromosomal alterations: a case-cohort study of Barrett's esophagusNew insights into the troubles of aneuploidyThe Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.Targeting aneuploid cancer cells.Complexity and dynamics of host-fungal interactions.Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leapA prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptationProtein disorder reduced in Saccharomyces cerevisiae to survive heat shock.Stress-induced loss of heterozygosity in Candida: a possible missing link in the ability to evolve.Cancer quasispecies and stem-like adaptive aneuploidy.Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.Establishment and characterization of a new feline mammary cancer cell line, FkMTp.Ploidy dynamics and evolvability in fungiHsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy.Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeastGenome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae.Mating of natural Saccharomyces cerevisiae strains for improved glucose fermentation and lignocellulosic inhibitor tolerance.3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations.The Role of Chromosomal Instability in Cancer and Therapeutic Responses.The Role of Centromere Defects in Cancer.
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Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 July 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
@en
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
@nl
type
label
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
@en
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
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prefLabel
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
@en
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
@nl
P2860
P1476
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer.
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P2093
P2860
P304
P356
10.1016/J.CEB.2010.06.003
P577
2010-07-23T00:00:00Z