GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics.
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Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective GABA(A) Receptor Modulators?Yellow fluorescent protein-based assay to measure GABA(A) channel activation and allosteric modulation in CHO-K1 cellsAllosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives.Esters of valerenic acid as potential prodrugs.Expression of gamma-aminobutyric acid type A receptor α2 subunit in the dorsal root ganglion of rats with sciatic nerve injury.The neurobiology of alcohol consumption and alcoholism: an integrative historyGABAA receptor subtype involvement in addictive behaviour.Functional characterization of the 1,5-benzodiazepine clobazam and its major active metabolite N-desmethylclobazam at human GABA(A) receptors expressed in Xenopus laevis oocytes.Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes.2'-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors.Reinforcing effects of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced rhesus monkeys.α4βδ GABAA receptors and tonic inhibitory current during adolescence: effects on mood and synaptic plasticityBenzodiazepine receptor ligands: a patent review (2006-2012).Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors.The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacym-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system.Organic and Peptidyl Constituents of Snake Venoms: The Picture Is Vastly More Complex Than We ImaginedEarly-life adversity selectively impairs α2-GABA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine
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P2860
GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@en
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@nl
type
label
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@en
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@nl
prefLabel
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@en
GABAA receptor subtype-selecti ...... s as non-sedating anxiolytics.
@nl
P1476
GABAA receptor subtype-selecti ...... ts as non-sedating anxiolytics
@en
P2093
John R Atack
P304
P356
10.2174/156802611795371350
P50
P577
2011-01-01T00:00:00Z