about
Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALSAutophagy and disease: always two sides to a problemAmino acids and mTORC1: from lysosomes to diseasePathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvationInhibition of LRRK2 kinase activity stimulates macroautophagyHdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid AccumulationTetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent AutophagyCalpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunctionAbsence of lipofuscin in motor neurons of SOD1-linked ALS mice.The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.Spinal autophagy is differently modulated in distinct mouse models of neuropathic pain.CLT1 targets angiogenic endothelium through CLIC1 and fibronectin.Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.Prions and the potential transmissibility of protein misfolding diseasesDeletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation.Role of plant autophagy in stress responseCircadian clocks and neurodegenerative diseases: time to aggregate?Measurement of autophagy flux in the nervous system in vivo.Resveratrol partially prevents rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through induction of heme oxygenase-1 dependent autophagyMisfolded protein aggregates: mechanisms, structures and potential for disease transmission.Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy.Regulation and function of autophagy during cell survival and cell death.A link between LRRK2, autophagy and NAADP-mediated endolysosomal calcium signalling.Protein quality control system in neurodegeneration: a healing company hard to beat but failure is fatal.DSSylation, a novel guide for protein degradation?Autophagic activity in neuronal cell deathAccumulation of autophagosomes confers cytotoxicity.To deliver or to degrade - an interplay of the ubiquitin-proteasome system, autophagy and vesicular transport in plants.Autophagy in neurodegenerative diseases: pathogenesis and therapy.Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects.A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease.Ultrastructural changes caused by Snf7 RNAi in larval enterocytes of western corn rootworm (Diabrotica virgifera virgifera Le Conte).Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.A new method to measure autophagy flux in the nervous system.New thoughts regarding Atg8 and ubiquitination.Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Protein misfolding disorders and macroautophagy.
@en
Protein misfolding disorders and macroautophagy.
@nl
type
label
Protein misfolding disorders and macroautophagy.
@en
Protein misfolding disorders and macroautophagy.
@nl
prefLabel
Protein misfolding disorders and macroautophagy.
@en
Protein misfolding disorders and macroautophagy.
@nl
P2093
P2860
P1476
Protein misfolding disorders and macroautophagy.
@en
P2093
David C Rubinsztein
Fiona M Menzies
Kevin Moreau
P2860
P304
P356
10.1016/J.CEB.2010.10.010
P577
2010-11-17T00:00:00Z