The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
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Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP BindingSensing of Mycobacterium tuberculosis and consequences to both host and bacillusCharacterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus ReplicationPotential of vesicular stomatitis virus as an oncolytic therapy for recurrent and drug-resistant ovarian cancer.Borrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokinesSTING mediates neuronal innate immune response following Japanese encephalitis virus infection.Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acidPivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effectsCells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs.Superresolution imaging of viral protein trafficking.Hantavirus regulation of type I interferon responses.Cutting Edge: Novel Tmem173 Allele Reveals Importance of STING N Terminus in Trafficking and Type I IFN Production.A novel pathway to detect and cope with exogenous dsDNA.STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection.Binding of bacterial secondary messenger molecule c di-GMP is a STING operationCyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasomeHSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.Cyclic di-nucleotides: new era for small molecules as adjuvants.Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.Disease mechanisms in rheumatology--tools and pathways: plasmacytoid dendritic cells and their role in autoimmune rheumatic diseases.DNA recognition in immunity and disease.Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1.HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response.Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?Regulating STING in health and diseaseSensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells.SILAC-based quantitative proteomic analysis of secretome of Marc-145 cells infected with porcine reproductive and respiratory syndrome virus.Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Abrogates NF-κB Activation in DNA Sensing Signal PathwayS6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control.Mutation Drivers of Immunological Responses to Cancer.Modulation of Stimulator of Interferon Genes (STING) Expression by Interferon-γ in Human Keratinocytes.Mitochondria-associated membranes (MAMs) and inflammation.InsP3R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca2+ elevation and TBK1 activity.STING-dependent signaling.Small-Molecule Targets in Tumor Immunotherapy
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The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 December 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@en
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
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type
label
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@en
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@nl
prefLabel
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@en
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@nl
P2860
P1476
The STING pathway and regulation of innate immune signaling in response to DNA pathogens.
@en
P2093
Glen N Barber
Hiroki Ishikawa
P2860
P2888
P304
P356
10.1007/S00018-010-0605-2
P577
2010-12-15T00:00:00Z
2011-04-01T00:00:00Z