about
Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.Synthetic and natural products as iron chelators.Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization.Halogenated 2'-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: relationship to intracellular redox activity.Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series.Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: structure-activity relationships of novel thiohydrazone analogues.Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.Novel diaroylhydrazine ligands as iron chelators: coordination chemistry and biological activity.Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.Electrochemically mediated enantioselective reduction of chiral sulfoxides.Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox ActivityC-substituted macrocycles as candidates for radioimmunotherapyStructurally reinforced tetraazamacrocyclic complexesTransition metal complexes as mediator-titrants in protein redox potentiometryHydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activity
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Philip C Sharpe
@nl
Philip C Sharpe
@sl
Philip C. Sharpe
@en
Philip C. Sharpe
@es
type
label
Philip C Sharpe
@nl
Philip C Sharpe
@sl
Philip C. Sharpe
@en
Philip C. Sharpe
@es
altLabel
Philip C. Sharpe
@en
prefLabel
Philip C Sharpe
@nl
Philip C Sharpe
@sl
Philip C. Sharpe
@en
Philip C. Sharpe
@es
P106
P1153
7103204044
P21
P31
P496
0000-0002-4770-4131