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Implementing prognostic and predictive biomarkers in CRC clinical trials.

Implementing prognostic and predictive biomarkers in CRC clinical trials.

http://www.wikidata.org/entity/Q37842126

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Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review Personalized treatment for advanced colorectal cancer: KRAS and beyond Identification of clinically relevant molecular subtypes in colorectal cancer: the dawning of a new era UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer Cancer research: from prognostic genes to therapeutic targets A rank-based transcriptional signature for predicting relapse risk of stage II colorectal cancer identified with proper data sources.Strategies for power calculations in predictive biomarker studies in survival data Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study A 5-gene classifier from the carcinoma-associated fibroblast transcriptomic profile and clinical outcome in colorectal cancer.Lung cancer transcriptomes refined with laser capture microdissection.The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer.KRAS mutation testing in metastatic colorectal cancer CT versus FDG-PET/CT response evaluation in patients with metastatic colorectal cancer treated with irinotecan and cetuximab.Prognostic role of ERCC1 in advanced non-small-cell lung cancer: a systematic review and meta-analysis.Systems vaccinology: its promise and challenge for HIV vaccine development.An update on miRNAs as biological and clinical determinants in colorectal cancer: a bench-to-bedside approach.Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis.Primary tumor location as a prognostic factor in metastatic colorectal cancer.Evidence for possible non-canonical pathway(s) driven early-onset colorectal cancer in India.ColoFinder: a prognostic 9-gene signature improves prognosis for 871 stage II and III colorectal cancer patients.Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy.Ginsenoside Rh2 alleviates tumor-associated depression in a mouse model of colorectal carcinoma Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer.Translating clinical research of Molecular Biology into a personalized, multidisciplinary approach of colorectal cancer patients Co-expression of Lgr5 and CXCR4 characterizes cancer stem-like cells of colorectal cancer.Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy.Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.Individualization of cancer treatment from radiotherapy perspective.MicroRNAs: relevant tools for a colorectal surgeon?Proteomics, genomics and transcriptomics: their emerging roles in the discovery and validation of colorectal cancer biomarkers.Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges.MiR-497 promotes metastasis of colorectal cancer cells through Nrdp1 inhibition.Role of Lgr5-positive cells in colorectal cancer.Astrocyte elevated gene-1 activates MMP9 to increase invasiveness of colorectal cancer.Novel markers for circulating tumor stem cells in colorectal carcinoma The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance.The role of microRNAs in colorectal liver metastasis: Important participants and potential clinical significances.Multi-omics landscapes of colorectal cancer subtypes discriminated by an individualized prognostic signature for 5-fluorouracil-based chemotherapy.Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.

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Implementing prognostic and predictive biomarkers in CRC clinical trials.

http://www.wikidata.org/entity/Q37842126

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 15 February 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@en

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@nl

type

label

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@en

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@nl

prefLabel

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@en

Implementing prognostic and predictive biomarkers in CRC clinical trials.

@nl

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NRCLINONC.2011.15

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Nature Reviews Clinical Oncology

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Implementing prognostic and predictive biomarkers in CRC clinical trials.

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Patrick G Johnston

http://www.w3.org/2001/XMLSchema#string

Richard C Turkington

http://www.w3.org/2001/XMLSchema#string

Sandra Van Schaeybroeck

http://www.w3.org/2001/XMLSchema#string

Wendy L Allen

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P2860

BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status.

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

Isolation of rare circulating tumour cells in cancer patients by microchip technology

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.

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222-232

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10.1038/NRCLINONC.2011.15

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