A fresh look at the mechanism of isoniazid-induced hepatotoxicity. - Wikidata - wikimedia - TriplyDB

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

http://www.wikidata.org/entity/Q37853833

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Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver Drug-induced hepatotoxicity: metabolic, genetic and immunological basis PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2 Pharmacogenomics of adverse drug reactions Isoniazid metabolism and hepatotoxicity Mechanism of isoniazid‐induced hepatotoxicity: then and now Relationship between characteristics of medications and drug-induced liver disease phenotype and outcome.Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing.A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.Pharmacogenetics of isoniazid-induced hepatotoxicity.Is the Prophylactic Use of Hepatoprotectants Necessary in Anti-Tuberculosis Treatment?Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats.Drug-Induced Liver Injury: Pattern Recognition and Future Directions.Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.Quantification of Hydrazine in Human Urine by HPLC-MS-MS.Changes in IL-2 and IL-10 during Chronic Administration of Isoniazid, Nevirapine, and Paracetamol in Rats.Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management.Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress.Drug-induced liver injury: Do we know everything?Genetic association studies in drug-induced liver injury.Transforming dietary peptides in promising lead compounds: the case of bioavailable carnosine analogs.Arylamine N-acetyltransferases: a structural perspective.Mechanisms of isoniazid-induced idiosyncratic liver injury: emerging role of mitochondrial stress.Hepatotoxicity mechanisms of isoniazid: A mini-review.The chemical, genetic and immunological basis of idiosyncratic drug-induced liver injury.Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation.Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?Accurate prediction of drug-induced liver injury using stem cell-derived populations.Might isoniazid plasma exposure be a valuable predictor of drug-related hepatotoxicity risk among adult patients with TB?Pharmacokinetics of the natural antibiotic negamycin.PharmGKB summary: isoniazid pathway, pharmacokinetics.Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial.Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients.Isoniazid hepatotoxicity: progress in understanding the immunologic component.CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug-induced hepatotoxicity: a nested case-control study.Lack of association between genetic polymorphisms of CYP3A4, CYP2C9 and CYP2C19 and antituberculosis drug-induced liver injury in a community-based Chinese population.The association between HLA-DQB1 polymorphism and antituberculosis drug-induced liver injury: a Case-Control Study.Lack of liver injury in Wistar rats treated with the combination of isoniazid and rifampicin.Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response.

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A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

http://www.wikidata.org/entity/Q37853833

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 16 March 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@en

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@nl

type

label

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@en

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@nl

prefLabel

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@en

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

@nl

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Clinical Pharmacology & Therapeutics

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A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

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I G Metushi

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J P Uetrecht

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P Cai

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T Nakagawa

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X Zhu

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P2860

Toxic hepatitis with isoniazid and rifampin. A meta-analysis.

Immunoallergic drug-induced liver injury in humans.

Involvement of the immune system in idiosyncratic drug reactions.

Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat.

D-penicillamine-induced autoimmunity: relationship to macrophage activation.

Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis.

Systemic lupus erythematosus induced by isoniazid.

The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury.

Increased risk of antituberculosis drug-induced hepatotoxicity in individuals with glutathione S-transferase M1 'null' mutation.

Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis.

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911-914

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scholarly article

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10.1038/CLPT.2010.355

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6

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89

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21412230

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