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Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers.The role of cancer stem cells and miRNAs in defining the complexities of brain metastasisAn Integrative Platform for Three-dimensional Quantitative Analysis of Spatially Heterogeneous Metastasis LandscapesDeconstructing the role of the ECM microenvironment on drug efficacy targeting MAPK signaling in a pre-clinical platform for cutaneous melanoma.Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brainMelanoma Brain Metastasis: Mechanisms, Models, and MedicinePerillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain MetastasesBRAF inhibitors and radiotherapy for melanoma brain metastases: potential advantages and disadvantages of combination therapyMultiorgan metastasis of human HER-2+ breast cancer in Rag2-/-;Il2rg-/- mice and treatment with PI3K inhibitorMRI Virtual Biopsy and Treatment of Brain Metastatic Tumors with Targeted Nanobioconjugates: Nanoclinic in the BrainElimination of Cancer Stem-Like Cells and Potentiation of Temozolomide Sensitivity by Honokiol in Glioblastoma Multiforme CellsBreast Cancer Brain Metastases: Clonal Evolution in Clinical Context.Clinical and molecular characteristics of HNSCC patients with brain metastases: a retrospective study.Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas.DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer.Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasisProfound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells.Lapatinib for the treatment of breast cancer in the People's Republic of China.Toward a drug development path that targets metastatic progression in osteosarcoma.Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabineαB-crystallin: a novel regulator of breast cancer metastasis to the brainPreservation of neurocognitive function and local control of 1 to 3 brain metastases treated with surgery and carmustine wafersMetastasis as a therapeutic target in prostate cancer: a conceptual framework.Brain neoplasms and coagulation-lessons from heterogeneity.Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin SExtracellular vesicles as prospective carriers of oncogenic protein signatures in adult and paediatric brain tumours.Longitudinal MRI evaluation of intracranial development and vascular characteristics of breast cancer brain metastases in a mouse model.A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrierTargeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.Efficacy of nab-paclitaxel plus trastuzumab in a long-surviving heavily pretreated HER2-positive breast cancer patient with brain metastasesRoles for endothelin receptor B and BCL2A1 in spontaneous CNS metastasis of melanoma.Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.(64)Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients.βIII-Tubulin Regulates Breast Cancer Metastases to the Brain.Therapeutic approaches for HER2-positive brain metastases: circumventing the blood-brain barrier.Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases.Opposing effects of pigment epithelium-derived factor on breast cancer cell versus neuronal survival: implication for brain metastasis and metastasis-induced brain damage.NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 April 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Brain metastases as preventive and therapeutic targets.
@en
Brain metastases as preventive and therapeutic targets.
@nl
type
label
Brain metastases as preventive and therapeutic targets.
@en
Brain metastases as preventive and therapeutic targets.
@nl
prefLabel
Brain metastases as preventive and therapeutic targets.
@en
Brain metastases as preventive and therapeutic targets.
@nl
P2093
P2860
P356
P1476
Brain metastases as preventive and therapeutic targets.
@en
P2093
Kevin A Camphausen
Patricia S Steeg
Quentin R Smith
P2860
P2888
P304
P356
10.1038/NRC3053
P407
P577
2011-04-07T00:00:00Z