Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer - Wikidata - wikimedia - TriplyDB

Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer

Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer

http://www.wikidata.org/entity/Q24621947

about

Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer.Novel delivery strategies for glioblastoma Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiency Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?The elephant in the room: do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties Monoclonal antibody-glial-derived neurotrophic factor fusion protein penetrates the blood-brain barrier in the mouse.Progress in the biological understanding and management of breast cancer-associated central nervous system metastases.Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.Emerging strategies for treating brain metastases from breast cancer.Specific amyloid β clearance by a catalytic antibody construct.Differential microstructure and physiology of brain and bone metastases in a rat breast cancer model by diffusion and dynamic contrast enhanced MRI.Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1.The biology of brain metastases-translation to new therapies Novel treatment strategies for brain tumors and metastases.NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer Preclinical approaches to study the biology and treatment of brain metastases.Treatment of Breast Cancer Brain Metastases.In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases due to Breast Cancer Improved anti-glioblastoma efficacy by IL-13Rα2 mediated copolymer nanoparticles loaded with paclitaxel.In vivo single scan detection of both iron-labeled cells and breast cancer metastases in the mouse brain using balanced steady-state free precession imaging at 1.5 T.Targeting tumor metastases: Drug delivery mechanisms and technologies.Breast cancer brain metastases: new directions in systemic therapy Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier.Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases.Biopharmaceutical drug targeting to the brain.Delivery of a peptide-drug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma.Targeted Nanotechnology in Glioblastoma Multiforme.Drug delivery to the CNS and polymeric nanoparticulate carriers.Brain metastases as preventive and therapeutic targets.Shuttle-mediated drug delivery to the brain.Improving the transport of chemotherapeutic drugs across the blood-brain barrier.Delivery of drugs to the brain via the blood brain barrier using colloidal carriers.Potential of anti-cancer therapy based on anti-miR-155 oligonucleotides in glioma and brain tumours.Overcoming the blood-brain barrier in chemotherapy treatment of pediatric brain tumors.Strategies for overcoming the blood-brain barrier for the treatment of brain metastases.Nanoparticles and the blood-brain barrier: advancing from in-vitro models towards therapeutic significance.Drug delivery and release systems for targeted tumor therapy.Strategies to target drugs to gliomas and CNS metastases of solid tumors.Targeting specific cells in the brain with nanomedicines for CNS therapies

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P2860

Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer

http://www.wikidata.org/entity/Q24621947

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Pharmaceutical Research

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Uptake of ANG1005, a novel pac ...... in metastases of breast cancer

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Diane Palmieri

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Fancy C Thomas

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Helen R Thorsheim

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Julie A Gaasch

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Kunal Taskar

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Patricia S Steeg

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Paul R Lockman

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Quentin R Smith

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Rajendar K Mittapalli

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Satyanarayana Goda

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P2860

The blood-brain barrier: bottleneck in brain drug development

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2

High transcytosis of melanotransferrin (P97) across the blood-brain barrier

Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells

Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.

Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.

Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.

Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: saturation kinetics and specificity.

Strategies to improve drug delivery across the blood-brain barrier.

Prophylactic cranial irradiation in extensive small-cell lung cancer.

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