Advances in the production and downstream processing of antibodies.
about
Rational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 MimeticsThe future of host cell protein (HCP) identification during process development and manufacturing linked to a risk-based management for their control.Seizing the strategic opportunities of emerging technologies by building up innovation system: monoclonal antibody development in China.Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza.Direct analysis of mAb aggregates in mammalian cell culture supernatant.Antibody therapy of pediatric B-cell lymphomaProteomic Analysis of Host Cell Protein Dynamics in the Culture Supernatants of Antibody-Producing CHO Cells.State-of-the-art in downstream processing of monoclonal antibodies: process trends in design and validation.Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools.Sophisticated Cloning, Fermentation, and Purification Technologies for an Enhanced Therapeutic Protein Production: A Review.Effects of lysosomal biotherapeutic recombinant protein expression on cell stress and protease and general host cell protein release in Chinese hamster ovary cells.An ultra scale-down approach identifies host cell protein differences across a panel of mAb producing CHO cell line variants.Evaluation of several protein a resins for application to multicolumn chromatography for the rapid purification of fed-batch bioreactors.High-throughput mAb expression and purification platform based on transient CHO.Development of monoclonal antibodies in China: overview and prospects.Host cell protein dynamics in recombinant CHO cells: impacts from harvest to purification and beyond.The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process.Development of adsorptive hybrid filters to enable two-step purification of biologics.Phospholipid imprinted polymers as selective endotoxin scavengers.Evaluating the efficiency of CHEF and CMV promoter with IRES and Furin/2A linker sequences for monoclonal antibody expression in CHO cells.Secretory production of single-chain antibody (scFv) in Brevibacillus choshinensis using novel fusion partner.Host cell proteins in biotechnology-derived products: A risk assessment framework.Single-step affinity purification of enzyme biotherapeutics: a platform methodology for accelerated process development.Advanced model-based control strategies for the intensification of upstream and downstream processing in mAb production.Trends in Upstream and Downstream Process Development for Antibody Manufacturing.Reduction of product-related species during the fermentation and purification of a recombinant IL-1 receptor antagonist at the laboratory and pilot scale.Characterization of Host Cell Proteins (HCPs) in CHO Cell Bioprocesses.Fully Automated Sample Preparation for Ultrafast N-Glycosylation Analysis of Antibody Therapeutics.Identification of high affinity HER2 binding antibodies using CHO Fab surface display.Evaluation of fluorescent dyes to measure protein aggregation within mammalian cell culture supernatants.Periodic counter-current chromatography -- design and operational considerations for integrated and continuous purification of proteins.Evolving trends in mAb production processes.Integrated flow-through purification for therapeutic monoclonal antibodies processing.Economics of recombinant antibody production processes at various scales: Industry-standard compared to continuous precipitation.Staphylococcus aureus toxin antibodies: Good companions of antibiotics and vaccines.UV resonance Raman spectroscopy: a process analytical tool for host cell DNA and RNA dynamics in mammalian cell lines
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P2860
Advances in the production and downstream processing of antibodies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 April 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Advances in the production and downstream processing of antibodies.
@en
Advances in the production and downstream processing of antibodies.
@nl
type
label
Advances in the production and downstream processing of antibodies.
@en
Advances in the production and downstream processing of antibodies.
@nl
prefLabel
Advances in the production and downstream processing of antibodies.
@en
Advances in the production and downstream processing of antibodies.
@nl
P1433
P1476
Advances in the production and downstream processing of antibodies.
@en
P2093
Gregory Zarbis-Papastoitsis
John H Chon
P304
P356
10.1016/J.NBT.2011.03.015
P577
2011-04-12T00:00:00Z