γ-Secretase-regulated mechanisms similar to notch signaling may play a role in signaling events, including APP signaling, which leads to Alzheimer's disease.
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The Amyloid Precursor Protein Controls PIKfyve FunctionRole of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer's diseaseInvestigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease.DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response.Wild-type neural progenitors divide and differentiate normally in an amyloid-rich environmentThe very many faces of presenilins and the γ-secretase complex.A truncated-Flt1 isoform of breast cancer cells is upregulated by Notch and downregulated by retinoic acid.Involvement of a conserved GFG motif region in substrate binding by RseP, an Escherichia coli S2P protease.
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γ-Secretase-regulated mechanisms similar to notch signaling may play a role in signaling events, including APP signaling, which leads to Alzheimer's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 April 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
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γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
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label
γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
@en
γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
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γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
@en
γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
@nl
P2093
P2860
P1476
γ-Secretase-regulated mechanis ...... leads to Alzheimer's disease.
@en
P2093
Chang-Sung Koh
Hisashi Nagase
Kohzo Nakayama
Takeshi Ohkawara
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P2888
P304
P356
10.1007/S10571-011-9688-Z
P577
2011-04-23T00:00:00Z