Aβ oligomer-induced synapse degeneration in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

http://www.wikidata.org/entity/Q37871455

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Synaptic Cell Adhesion Molecules in Alzheimer's Disease Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics EphBs: an integral link between synaptic function and synaptopathies Common transcriptional signatures in brain tissue from patients with HIV-associated neurocognitive disorders, Alzheimer's disease, and Multiple Sclerosis Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β.Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease.Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats.Multifunctional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in Alzheimer's disease mouse models.Nanodiscs as a new tool to examine lipid-protein interactions.Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide.Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.Synaptic changes in the dentate gyrus of APP/PS1 transgenic mice revealed by electron microscopy.The protein oxidation repair enzyme methionine sulfoxide reductase a modulates Aβ aggregation and toxicity in vivo.Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease.Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease Soluble Aβ oligomer production and toxicity.Amyloid-β oligomers induce differential gene expression in adult human brain slices.Synaptic mitochondrial pathology in Alzheimer's disease Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-β peptide oligomers.Amyloid deposition and advanced age fails to induce Alzheimer's type progression in a double knock-in mouse model Rationally Designed CeNP@MnMoS4 Core-Shell Nanoparticles for Modulating Multiple Facets of Alzheimer's Disease.Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD.Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X.Presynaptic Aβ40 prevents synapse addition in the adult Drosophila neuromuscular junction.Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe.Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease.Using Pittsburgh Compound B for in vivo PET imaging of fibrillar amyloid-beta.Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits.Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin Inhibitors In vitro prion-like behaviour of TDP-43 in ALS.Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine--searching for the connections Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease.

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Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

http://www.wikidata.org/entity/Q37871455

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 03 May 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@en

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@nl

type

label

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@en

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@nl

prefLabel

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@en

Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

@nl

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S10571-011-9691-4

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Cellular and Molecular Neurobiology

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Aβ oligomer-induced synapse degeneration in Alzheimer's disease.

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Jason Pitt

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Kyle C Wilcox

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Pascale N Lacor

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William L Klein

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P2860

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

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s10571-011-9691-4

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939-948

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scholarly article

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10.1007/S10571-011-9691-4

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6

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31

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2011-05-03T00:00:00Z

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51094081

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21538118

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Alzheimer's disease

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3146579

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