Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.
about
Lithium: the pharmacodynamic actions of the amazing ionFKBP12 regulates the localization and processing of amyloid precursor protein in human cell linesNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismRapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceMethylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activityFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesFocus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's DiseaseOlive Oil and the Hallmarks of AgingMolecular Targets in Alzheimer's Disease: From Pathogenesis to TherapeuticsThe Function of Autophagy in Neurodegenerative DiseasesThe Role of Inflammatory Mediators in the Pathogenesis of Alzheimer's DiseaseMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalDual roles for autophagy: degradation and secretion of Alzheimer's disease Aβ peptideFK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation?Autophagy and neurodegenerationThe lysosome: from waste bag to potential therapeutic targetMetformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathySpatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatmentThe anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complexPotential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disordersTherapeutic Targeting of AutophagyACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseAutophagy in neurodegenerative diseases: from mechanism to therapeutic approachThe role of mTOR signaling in Alzheimer diseaseAutophagy in Neurodegenerative Diseases and Metal NeurotoxicityPim1 inhibition as a novel therapeutic strategy for Alzheimer's diseaseRapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restrictionSingle-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's diseaseRapamycin attenuates the progression of tau pathology in P301S tau transgenic miceCilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal CellsThe zinc dyshomeostasis hypothesis of Alzheimer's diseasemTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease.Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseasemTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.PICALM modulates autophagy activity and tau accumulation.Regulation of amyloid precursor protein processing by the Beclin 1 complexLC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.Rapamycin extends life and health in C57BL/6 miceNovel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.
P2860
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P2860
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Molecular interplay between ma ...... fects on cognitive impairments
@nl
Molecular interplay between ma ...... ects on cognitive impairments.
@ast
Molecular interplay between ma ...... ects on cognitive impairments.
@en
type
label
Molecular interplay between ma ...... fects on cognitive impairments
@nl
Molecular interplay between ma ...... ects on cognitive impairments.
@ast
Molecular interplay between ma ...... ects on cognitive impairments.
@en
prefLabel
Molecular interplay between ma ...... fects on cognitive impairments
@nl
Molecular interplay between ma ...... ects on cognitive impairments.
@ast
Molecular interplay between ma ...... ects on cognitive impairments.
@en
P2093
P2860
P3181
P356
P1476
Molecular interplay between ma ...... ects on cognitive impairments.
@en
P2093
Antonella Caccamo
Arlan Richardson
Randy Strong
Salvatore Oddo
Smita Majumder
P2860
P304
13107-13120
P3181
P356
10.1074/JBC.M110.100420
P407
P577
2010-02-23T00:00:00Z