Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents.
about
Kappa opioid antagonists: past successes and future prospectsDesign, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists.Peptides as receptor ligand drugs and their relationship to G-coupled signal transduction.Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5.Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists.14-Alkoxy- and 14-acyloxypyridomorphinans: μ agonist/δ antagonist opioid analgesics with diminished tolerance and dependence side effectsActivation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic PainDevelopment of κ opioid receptor antagonists.Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathwayBinding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mBinding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation.The design and synthesis of a novel quinolizidine template for potent opioid and opioid receptor-like (ORL1, NOP) receptor ligands.Aminothiazolomorphinans with mixed κ and μ opioid activity.14-O-Heterocyclic-substituted naltrexone derivatives as non-peptide mu opioid receptor selective antagonists: design, synthesis, and biological studies.Opioid receptor selectivity profile change via isosterism for 14-O-substituted naltrexone derivatives.[6,7]-heterocycle-fused 14-hydroxymorphinan derivatives: design, synthesis, and opioid receptor activity.Involvement of mu-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats.The stereoisomer (+)-naloxone potentiates G-protein coupling and feeding associated with stimulation of mu opioid receptors in the parabrachial nucleus.Opioid receptors mediate inotropic and depressor effects of apelin in rats with 2K1C-induced chronic renovascular hypertension.Delta(2)-opioid receptor mediation of morphine-induced CCK release in the frontal cortex of the freely moving rat.
P2860
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P2860
Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Selective opioid receptor agon ...... potential therapeutic agents.
@en
Selective opioid receptor agon ...... potential therapeutic agents.
@nl
type
label
Selective opioid receptor agon ...... potential therapeutic agents.
@en
Selective opioid receptor agon ...... potential therapeutic agents.
@nl
prefLabel
Selective opioid receptor agon ...... potential therapeutic agents.
@en
Selective opioid receptor agon ...... potential therapeutic agents.
@nl
P356
P1476
Selective opioid receptor agon ...... potential therapeutic agents.
@en
P2093
Leander JD
Zimmerman DM
P304
P356
10.1021/JM00165A002
P407
P577
1990-03-01T00:00:00Z