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New look at the role of progerin in skin agingRecent advances in understanding the role of lamins in health and diseaseAge-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteriesPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesGlucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cellsMicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis.The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell LineagesA filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction.Calcium causes a conformational change in lamin A tail domain that promotes farnesyl-mediated membrane association.Role of the nuclear envelope in the pathogenesis of age-related bone loss and osteoporosis.An upregulation in the expression of vanilloid transient potential channels 2 enhances hypotonicity-induced cytosolic Ca²⁺ rise in human induced pluripotent stem cell model of Hutchinson-Gillford Progeria.Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome.Mitotic centromere-associated kinase (MCAK/Kif2C) regulates cellular senescence in human primary cells through a p53-dependent pathway.Premature and accelerated aging: HIV or HAART?Disruption of lamin B1 and lamin B2 processing and localization by farnesyltransferase inhibitors.Interfacial binding and aggregation of lamin A tail domains associated with Hutchinson-Gilford progeria syndrome.Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin.Age-dependent changes of nuclear morphology are uncoupled from longevity in Caenorhabditis elegans IGF/insulin receptor daf-2 mutants.Cardioprotection by farnesol: role of the mevalonate pathway.Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells.N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.HJURP regulates cellular senescence in human fibroblasts and endothelial cells via a p53-dependent pathway.Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Lamin A, farnesylation and aging
@en
Lamin A, farnesylation and aging.
@nl
type
label
Lamin A, farnesylation and aging
@en
Lamin A, farnesylation and aging.
@nl
prefLabel
Lamin A, farnesylation and aging
@en
Lamin A, farnesylation and aging.
@nl
P2860
P1476
Lamin A, farnesylation and aging
@en
P2093
Lucio Comai
Sita Reddy
P2860
P356
10.1016/J.YEXCR.2011.08.009
P407
P577
2011-08-16T00:00:00Z