Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.
about
Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisGlobal proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogueA combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins.Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues.Protein prenylation: enzymes, therapeutics, and biotechnology applications.Use of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasionSynthesis of Peptides Containing C-Terminal Esters Using Trityl Side-Chain Anchoring: Applications to the Synthesis of C-Terminal Ester Analogs of the Saccharomyces cerevisiae Mating Pheromone a-FactorDiazirine-containing photoactivatable isoprenoid: synthesis and application in studies with isoprenylcysteine carboxyl methyltransferase6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning.Lipids beyond membranes; farnesylation targets Spindly to kinetochoresExploring the putative self-binding property of the human farnesyltransferase alpha-subunit.Development of the Regiodivergent Asymmetric Prenylation of 3-Substituted Oxindoles.The Prenylated Proteome of Plasmodium falciparum Reveals Pathogen-specific Prenylation Activity and Drug Mechanism-of-action.Applying the prodrug strategy to α-phosphonocarboxylate inhibitors of Rab GGTase--synthesis and stability studies.Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.a-Factor: a chemical biology tool for the study of protein prenylation.The Many Faces of Rap1 GTPase
P2860
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P2860
Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Prenyltransferase Inhibitors: ...... ancer to Parasitic Infections.
@en
type
label
Prenyltransferase Inhibitors: ...... ancer to Parasitic Infections.
@en
prefLabel
Prenyltransferase Inhibitors: ...... ancer to Parasitic Infections.
@en
P2860
P356
P1433
P1476
Prenyltransferase Inhibitors: ...... ancer to Parasitic Infections.
@en
P2093
Joshua D Ochocki
Mark D Distefano
P2860
P304
P356
10.1039/C2MD20299A
P577
2013-03-01T00:00:00Z