Platensimycin and platencin: promising antibiotics for future application in human medicine.
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Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH)Antibiotics and bacterial resistance in the 21st century.Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureusTiter improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026.Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.Microbial synthetic biology for human therapeutics.Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin.A Facile Semi-Synthetic Approach towards Halogen-Substituted Aminobenzoic Acid Analogues of Platensimycin.Advances in MRSA drug discovery: where are we and where do we need to be?Developing new antibacterials through natural product research.Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid.Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600.Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products.Antibacterial and cytotoxic activity from the extract and fractions of a marine derived bacterium from the Streptomyces genus.Xanthone derivatives could be potential antibiotics: virtual screening for the inhibitors of enzyme I of bacterial phosphoenolpyruvate-dependent phosphotransferase system.Novel systemic antibiotics in dermatology.Development of a chemically defined medium for the production of the antibiotic platensimycin by Streptomyces platensis.Enterococcus faecalis and pathogenic streptococci inactivate daptomycin by releasing phospholipids.
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Platensimycin and platencin: promising antibiotics for future application in human medicine.
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article científic
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Platensimycin and platencin: p ...... application in human medicine.
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Platensimycin and platencin: p ...... application in human medicine.
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Platensimycin and platencin: p ...... application in human medicine.
@en
Platensimycin and platencin: p ...... application in human medicine.
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Platensimycin and platencin: p ...... application in human medicine.
@en
Platensimycin and platencin: p ...... application in human medicine.
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Platensimycin and platencin: p ...... application in human medicine.
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Arnold L Demain
Evan Martens
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P2888
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10.1038/JA.2011.80
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2011-09-14T00:00:00Z