Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.
about
Antibacterial Discovery and Development: From Gene to Product and BackSynthetic biology to access and expand nature's chemical diversityCurrent approaches to exploit actinomycetes as a source of novel natural products.Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.Metabolic engineering for the production of natural products.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesMolecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus.Strain prioritization for natural product discovery by a high-throughput real-time PCR method.Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, I and J.Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.Refactoring the nitrogen fixation gene cluster from Klebsiella oxytocaTiter improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026.Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.Biosynthetic Origin of the Ether Ring in Platensimycin.In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin.Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulationStrain improvement in actinomycetes in the postgenomic era.The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.Natural products and Pharma 2011: strategic changes spur new opportunities.Platensimycin and platencin: promising antibiotics for future application in human medicine.Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis.A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600.Engineering microbial hosts for production of bacterial natural productsAdvancement in bioprocess technology: parallels between microbial natural products and cell culture biologics.Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.A concise ring-expansion route to the compact core of platensimycin.Development of a chemically defined medium for the production of the antibiotic platensimycin by Streptomyces platensis.Actinomycetes: still a source of novel antibiotics.New Kid on the Block: LmbU Expands the Repertoire of Specialized Metabolic Regulators in Streptomyces.Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.Biosynthesis of thiocarboxylic acid-containing natural products.Regulation of antibiotic biosynthesis in actinomycetes: Perspectives and challenges
P2860
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P2860
Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Engineered Streptomyces platen ...... s platensimycin and platencin.
@ast
Engineered Streptomyces platen ...... s platensimycin and platencin.
@en
Engineered Streptomyces platen ...... s platensimycin and platencin.
@nl
type
label
Engineered Streptomyces platen ...... s platensimycin and platencin.
@ast
Engineered Streptomyces platen ...... s platensimycin and platencin.
@en
Engineered Streptomyces platen ...... s platensimycin and platencin.
@nl
prefLabel
Engineered Streptomyces platen ...... s platensimycin and platencin.
@ast
Engineered Streptomyces platen ...... s platensimycin and platencin.
@en
Engineered Streptomyces platen ...... s platensimycin and platencin.
@nl
P2093
P2860
P356
P1476
Engineered Streptomyces platen ...... cs platensimycin and platencin
@en
P2093
Michael J Smanski
Scott R Rajski
P2860
P304
P356
10.1128/AAC.01358-08
P407
P577
2009-01-21T00:00:00Z