Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins. - Wikidata - wikimedia - TriplyDB

Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.

Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.

http://www.wikidata.org/entity/Q37960450

about

Role of Hedgehog Signaling Pathway in NASH T-cells play the classics with a different spin Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways Smoothened goes molecular: new pieces in the hedgehog signaling puzzle Gi proteins mediate activation of the canonical hedgehog pathway in the myocardium.Sonic hedgehog signaling in the lung. From development to disease.Discovery of small-molecule modulators of the Sonic Hedgehog pathway.Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.MiR-218 inhibits multidrug resistance (MDR) of gastric cancer cells by targeting Hedgehog/smoothened.The small GTPase Rap1 is a modulator of Hedgehog signaling.Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation The transition from differentiation to growth during dermomyotome-derived myogenesis depends on temporally restricted hedgehog signaling.Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells Heterotrimeric G protein signaling in polycystic kidney disease Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling.Rab23's genetic structure, function and related diseases: a review.Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment.Canonical and non-canonical Hedgehog signalling and the control of metabolism.Decoding Ci: from partial degradation to inhibition.Hedgehog and Resident Vascular Stem Cell Fate.The role of taurine in improving neural stem cells proliferation and differentiation.Sonic hedgehog signaling in kidney fibrosis: a master communicator.Astrocyte-derived sonic hedgehog contributes to angiogenesis in brain microvascular endothelial cells via RhoA/ROCK pathway after oxygen-glucose deprivation.Hedgehog signalling in liver pathophysiology.The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development.Rab23 is overexpressed in human astrocytoma and promotes cell migration and invasion through regulation of Rac1.Stathmin inhibits proliferation and differentiation of dental pulp stem cells via sonic hedgehog/Gli.Primary Cilia as a Signaling Platform for Control of Energy Metabolism.Differential Cellular Responses to Hedgehog Signalling in Vertebrates-What is the Role of Competence?

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P2860

Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.

http://www.wikidata.org/entity/Q37960450

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

@zh-my

2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

@en

Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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SCISIGNAL.2002396

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Science Signaling

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Sonic Hedgehog activates the G ...... of smoothened to Gi proteins.

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Ariel H Polizio

http://www.w3.org/2001/XMLSchema#string

David R Manning

http://www.w3.org/2001/XMLSchema#string

Natalia A Riobo

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Pilar Chinchilla

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Xiaolen Chen

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P2860

Small molecule modulation of Smoothened activity

Vertebrate Smoothened functions at the primary cilium.

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice

Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines.

The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog.

Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling.

Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration.

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10.1126/SCISIGNAL.2002396

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200

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22114142

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