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Probing heterotrimeric G protein activation: applications to biased ligands.

Probing heterotrimeric G protein activation: applications to biased ligands.

http://www.wikidata.org/entity/Q37974268

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Cardiac cAMP: production, hydrolysis, modulation and detection A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways Propensity scores for prediction and characterization of bioluminescent proteins from sequences.Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.How much do we know about the coupling of G-proteins to serotonin receptors?Drug Binding Poses Relate Structure with Efficacy in the μ Opioid Receptor.β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1.Biarsenical ligands bind to endogenous G-protein α-subunits and enable allosteric sensing of nucleotide binding.Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression.[G-protein-coupled receptors plasticity and signalling].

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Probing heterotrimeric G protein activation: applications to biased ligands.

http://www.wikidata.org/entity/Q37974268

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article científic

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Probing heterotrimeric G protein activation: applications to biased ligands.

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Probing heterotrimeric G protein activation: applications to biased ligands.

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type

label

Probing heterotrimeric G protein activation: applications to biased ligands.

@en

Probing heterotrimeric G protein activation: applications to biased ligands.

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prefLabel

Probing heterotrimeric G protein activation: applications to biased ligands.

@en

Probing heterotrimeric G protein activation: applications to biased ligands.

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138161212799040466

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Current Pharmaceutical Design

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Probing heterotrimeric G protein activation: applications to biased ligands

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Aude Saulière

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Segolene Galandrin

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P2860

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

Purification of the regulatory component of adenylate cyclase

Translocation of arrestin induced by human A(3) adenosine receptor ligands in an engineered cell line: comparison with G protein-dependent pathways

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

The G protein-coupled receptor repertoires of human and mouse

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

The 2.0 A crystal structure of a heterotrimeric G protein

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128-144

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scholarly article

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10.2174/138161212799040466

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2

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18

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Jean-Michel Sénard

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2012-01-01T00:00:00Z

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221733274

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22229559

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3389521

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