Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
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Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activityStructural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loopsPivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetateDistinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicolEvidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complexRegulation of pyruvate dehydrogenase activity through phosphorylation at multiple sitesInteraction between the individual isoenzymes of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase complexThe remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexesStructural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complexSubunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complexStructure of pyruvate dehydrogenase kinase. Novel folding pattern for a serine protein kinaseAn amino acid substitution in the pyruvate dehydrogenase E1 alpha gene, affecting mitochondrial import of the precursor proteinPyruvate dehydrogenase E1 alpha deficiency: males and females differ yet againDifferential epitope mapping of antibodies to PDC-E2 in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation and primary biliary cirrhosisCrystal structure of an asymmetric complex of pyruvate dehydrogenase kinase 3 with lipoyl domain 2 and its biological implicationsLow-temperature carbon utilization is regulated by novel gene activity in the heart of a hibernating mammalHuman Metabolic Enzymes Deficiency: A Genetic Mutation Based ApproachRetinol as electron carrier in redox signaling, a new frontier in vitamin A researchAn update on the role of mitochondrial α-ketoglutarate dehydrogenase in oxidative stressStructures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains.Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferaseCrystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional ImplicationsThe structural basis for substrate versatility of chloramphenicol acetyltransferase CATIInsight to the Interaction of the Dihydrolipoamide Acetyltransferase (E2) Core with the Peripheral Components in the Escherichia coli Pyruvate Dehydrogenase Complex via Multifaceted Structural Approaches3D electron microscopy reveals the variable deposition and protein dynamics of the peripheral pyruvate dehydrogenase component about the core.On the unique structural organization of the Saccharomyces cerevisiae pyruvate dehydrogenase complexDirect imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP)An essential role of Glu-243 and His-239 in the phosphotransfer reaction catalyzed by pyruvate dehydrogenase kinaseEvidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamilyChanges in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brainAncestral genome reconstruction identifies the evolutionary basis for trait acquisition in polyphosphate accumulating bacteriaAntiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.Cloning and characterization of the dihydrolipoamide S-acetyltransferase subunit of the plastid pyruvate dehydrogenase complex (E2) from Arabidopsis.Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis.Pyruvate dehydrogenase kinase as a potential therapeutic target for malignant gliomas.Decarboxylation of pyruvate to acetaldehyde for ethanol production by hyperthermophilesThe pyruvate dehydrogenase complexes: structure-based function and regulation.Diversity in functional organization of class I and class II biotin protein ligase.Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis.Identification of Sinorhizobium meliloti genes regulated during symbiosis.
P2860
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P2860
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@en
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@nl
type
label
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@en
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@nl
prefLabel
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@en
Molecular biology and biochemistry of pyruvate dehydrogenase complexes.
@nl
P1433
P1476
Molecular biology and biochemistry of pyruvate dehydrogenase complexes
@en
P2093
P304
P356
10.1096/FASEBJ.4.14.2227213
P407
P577
1990-11-01T00:00:00Z