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Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleasesTargeting serous epithelial ovarian cancer with designer zinc finger transcription factorsModeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future ConcernsGenome Engineering with TALE and CRISPR Systems in NeuroscienceGenome Editing in C. elegans and Other Nematode SpeciesPluripotent stem cells and gene therapyRecombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyondFive phylogenetically close rice SWEET genes confer TAL effector-mediated susceptibility to Xanthomonas oryzae pv. oryzae.ASGARD: an open-access database of annotated transcriptomes for emerging model arthropod speciesTALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicityMouse genetics: catalogue and scissorsScreening methods to identify TALEN-mediated knockout mice.Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.Locus-specific editing of histone modifications at endogenous enhancersTALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery.Chimeric TALE recombinases with programmable DNA sequence specificityWriting and rewriting the epigenetic code of cancer cells: from engineered proteins to small moleculesDirect observation of TALE protein dynamics reveals a two-state search mechanismGenome editing and the next generation of antiviral therapy.Gene- and protein-delivered zinc finger-staphylococcal nuclease hybrid for inhibition of DNA replication of human papillomavirus.TALEN-based gene disruption in the dengue vector Aedes aegypti.Cancer translocations in human cells induced by zinc finger and TALE nucleasesAn efficient strategy for TALEN-mediated genome engineering in DrosophilaTAL effector specificity for base 0 of the DNA target is altered in a complex, effector- and assay-dependent manner by substitutions for the tryptophan in cryptic repeat -1.Tandem repeat modification during double-strand break repair induced by an engineered TAL effector nuclease in zebrafish genome.Development of a targeted flip-in system in avian DT40 cells.Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription RegulatorsA 3D human neural cell culture system for modeling Alzheimer's disease.Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors.Beyond the mouse monopoly: studying the male germ line in domestic animal models.Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents.Alzheimer's disease in a dish: promises and challenges of human stem cell models.Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotesRobust, synergistic regulation of human gene expression using TALE activatorsDifferential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.Animal models of GWAS-identified type 2 diabetes genes.A validated cellular biobank for β-thalassemia.Advances in Mammalian cell line development technologies for recombinant protein production.Fast quantitative real-time PCR-based screening for common chromosomal aneuploidies in mouse embryonic stem cells.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
TALE nucleases: tailored genome engineering made easy.
@en
TALE nucleases: tailored genome engineering made easy.
@nl
type
label
TALE nucleases: tailored genome engineering made easy.
@en
TALE nucleases: tailored genome engineering made easy.
@nl
prefLabel
TALE nucleases: tailored genome engineering made easy.
@en
TALE nucleases: tailored genome engineering made easy.
@nl
P1476
TALE nucleases: tailored genome engineering made easy.
@en
P2093
Claudio Mussolino
P304
P356
10.1016/J.COPBIO.2012.01.013
P577
2012-02-17T00:00:00Z