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Cancer translocations in human cells induced by zinc finger and TALE nucleases

Cancer translocations in human cells induced by zinc finger and TALE nucleases

http://www.wikidata.org/entity/Q34660198

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Engineered Swine Models of Cancer Making designer mutants in model organisms Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9.TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome.Genomic editing tools to model human diseases with isogenic pluripotent stem cells.A Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy.Deciphering the pathogenic consequences of chromosomal aberrations in human genetic disease.Synthetic biology for therapeutic applications.Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells.Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.Creating cancer translocations in human cells using Cas9 DSBs and nCas9 paired nicks.Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks.Pluripotent stem cell applications for regenerative medicine Targeted Chromosomal Translocations and Essential Gene Knockout Using CRISPR/Cas9 Technology in Caenorhabditis elegans.TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality.Accelerated genome engineering through multiplexing.Genome engineering: Drosophila melanogaster and beyond Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joining A genome editing primer for the hematologist Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish.Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila.New and TALENted genome engineering toolbox.Various applications of TALEN- and CRISPR/Cas9-mediated homologous recombination to modify the Drosophila genome.Nuclease-mediated genome editing: At the front-line of functional genomics technology.Is non-homologous end-joining really an inherently error-prone process?TALEN-mediated genome editing: prospects and perspectives.Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes.TALEN-mediated genome engineering to generate targeted mice.Utilization of TALEN and CRISPR/Cas9 technologies for gene targeting and modification.CRISPR-Cas9 systems: versatile cancer modelling platforms and promising therapeutic strategies.Proteomics in the genome engineering era.An overview of chronic myeloid leukemia and its animal models.From hacking the human genome to editing organs Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.

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Cancer translocations in human cells induced by zinc finger and TALE nucleases

http://www.wikidata.org/entity/Q34660198

description

2013 nî lūn-bûn

@nan

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年学术文章

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2013年学术文章

@zh-cn

2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

@yue

name

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@ast

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@en

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@nl

type

label

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@ast

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@en

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@nl

prefLabel

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@ast

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@en

Cancer translocations in human cells induced by zinc finger and TALE nucleases

@nl

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Genome Research

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Cancer translocations in human cells induced by zinc finger and TALE nucleases

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Carine Giovannangeli

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George E Katibah

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Hind Ghezraoui

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Lei Zhang

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Loic Perrouault

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Maria Jasin

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Marion Piganeau

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Mark Tomishima

http://www.w3.org/2001/XMLSchema#string

Michael C Holmes

http://www.w3.org/2001/XMLSchema#string

Oliver René

http://www.w3.org/2001/XMLSchema#string

P2860

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation

Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication

Targeted chromosomal deletions in human cells using zinc finger nucleases

Chromosome translocation based on illegitimate recombination in human tumors

Derivation of multipotent mesenchymal precursors from human embryonic stem cells

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

IgH class switching and translocations use a robust non-classical end-joining pathway

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation

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1182-1193

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10.1101/GR.147314.112

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7

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Jean-Paul Concordet

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2013-04-08T00:00:00Z

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236140273

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