Disintegrins: a family of integrin inhibitory proteins from viper venoms.
about
Conservation of pregnancy-specific glycoprotein (PSG) N domains following independent expansions of the gene families in rodents and primatesCloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS familyInteraction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domainsA novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancersConformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMRThe Promise of Integrins as Effective Targets for Anticancer AgentsA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsAntitumoral activity of snake venom proteins: new trends in cancer therapyInsight into the sialome of the castor bean tick, Ixodes ricinus.Three-dimensional structure of the RGD-containing neurotoxin homologue dendroaspinEchistatin: the refined structure of a disintegrin in solution by 1H NMR and restrained molecular dynamicsAnti-thrombotic agents derived from snake venom proteinsMetalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction SitesFertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilizationThe lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1Upregulation of ADAM19 in chronic allograft nephropathyPharmacological characterization and antithrombotic effect of agkistin, a platelet glycoprotein Ib antagonistEvaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesionArg-Tyr-Asp (RYD) and Arg-Cys-Asp (RCD) motifs in dendroaspin promote selective inhibition of beta1 and beta3 integrinsPositional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3Discovery of platyhelminth-specific α/β-integrin families and evidence for their role in reproduction in Schistosoma mansoniA family of cellular proteins related to snake venom disintegrinsCellular localization of the disintegrin CRII-7/rMDC15 mRNA in rat PNS and CNS and regulated expression in postnatal development and after nerve injuryVicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activitiesDestabilizing loop swaps in the CDRs of an immunoglobulin VL domain.Evidence that distinct states of the integrin alpha6beta1 interact with laminin and an ADAM.Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.Function of disintegrin-like/cysteine-rich domains of atrolysin A. Inhibition of platelet aggregation by recombinant protein and peptide antagonists.BJ46a, a snake venom metalloproteinase inhibitor. Isolation, characterization, cloning and insights into its mechanism of action.Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells.A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis.The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Improvements in endotoxemic syndromes using a disintegrin, rhodostomin, through integrin αvβ3-dependent pathway.Snake venom hemorrhagins.Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition.Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus).Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cellsSnake venom: From fieldwork to the clinic: Recent insights into snake biology, together with new technology allowing high-throughput screening of venom, bring new hope for drug discovery.
P2860
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P2860
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@en
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@nl
type
label
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@en
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@nl
prefLabel
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@en
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@nl
P2093
P1476
Disintegrins: a family of integrin inhibitory proteins from viper venoms.
@en
P2093
M A Polokoff
P A Friedman
S Niewiarowski
P304
P356
10.3181/00379727-195-43129B
P577
1990-11-01T00:00:00Z