Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.

Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.

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http://www.wikidata.org/entity/Q37990962
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitorsExploration of Novel Inhibitors for Bruton's Tyrosine Kinase by 3D QSAR Modeling and Molecular Dynamics SimulationCovalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition ReactionsTargeting Btk/Etk of prostate cancer cells by a novel dual inhibitorDiscovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.Bruton's TK inhibitors: structural insights and evolution of clinical candidates.Prolonged and tunable residence time using reversible covalent kinase inhibitors.Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression.Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.New drug design with covalent modifiers.Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.Development of a pharmacodynamic assay based on PLCγ2 phosphorylation for quantifying spleen tyrosine kinase (SYK)-Bruton's tyrosine kinase (BTK) signaling.Discovery of Novel Bruton's Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold.QSAR analysis of nicotinamidic compounds and design of potential Bruton's tyrosine kinase (Btk) inhibitors.
P2860

Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.

Item
http://www.wikidata.org/entity/Q37990962
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
@id
artikull shkencor
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artículo científico
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Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@en
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@nl
type
label
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@en
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@nl
prefLabel
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@en
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Bruton's tyrosine kinase inhib ...... eases and B cell malignancies.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921