SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.
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SIRT3 as a Regulator of Non-alcoholic Fatty Liver DiseaseFunction of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseThe hallmarks of agingMitochondrial dysfunction in cardiac agingMitochondrial stress signaling promotes cellular adaptationsAge-related decrease in the mitochondrial sirtuin deacetylase Sirt3 expression associated with ROS accumulation in the auditory cortex of the mimetic aging rat model.Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patientsSirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.Loss of Sirt3 limits bone marrow cell-mediated angiogenesis and cardiac repair in post-myocardial infarction.Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress.Low SIRT3 expression correlates with poor differentiation and unfavorable prognosis in primary hepatocellular carcinoma.Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression.Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes.Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studiesSIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells.Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss.SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin.Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilizationPerm1 enhances mitochondrial biogenesis, oxidative capacity, and fatigue resistance in adult skeletal muscle.Sirtuins Function as the Modulators in Aging-related Diseases in Common or RespectivelySirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice.Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human MelanomaSirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes.The role of mitochondrial DNA mutations and free radicals in disease and ageingCrosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.BET1L and TNRC6B associate with uterine fibroid risk among European Americans.SIRT1 attenuates high glucose-induced insulin resistance via reducing mitochondrial dysfunction in skeletal muscle cells.Sirtuin 3: A major control point for obesity-related metabolic diseases?RelB: an outlier in leukocyte biology.Sirtuin 3 deficiency does not augment hypoxia-induced pulmonary hypertension.Sirtuin 3 is required for osteogenic differentiation through maintenance of PGC-1ɑ-SOD2-mediated regulation of mitochondrial function.Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models.Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.NAD and ADP-ribose metabolism in mitochondria.Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction.Sirtuins' modulation of autophagy.The diversity of histone versus nonhistone sirtuin substrates.Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria.
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SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.
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type
label
SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.
@en
prefLabel
SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging.
@en
P356
P1433
P1476
SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging
@en
P2093
Albert Giralt
Francesc Villarroya
P356
10.1042/BJ20120030
P407
P577
2012-05-01T00:00:00Z