Tumorigenesis by slow-transforming retroviruses--an update.
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Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrationsRetroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frameHIV-1 promotor insertion revealed by selective detection of chimeric provirus-host gene transcriptsbic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNAMeis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 miceExpression of the putative proto-oncogene His-1 in normal and neoplastic tissuesNf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemiaSint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene familyIntroduction of a cis-acting mutation in the capsid-coding gene of moloney murine leukemia virus extends its leukemogenic propertiesGris1, a new common integration site in Graffi murine leukemia virus-induced leukemias: overexpression of a truncated cyclin D2 due to alternative splicing.Genetic profile of insertion mutations in mouse leukemias and lymphomas.Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expressionIsolation of new oncogenic forms of the murine c-fms gene.Novel integration sites at the distal 3' end of the c-myb locus in retrovirus-induced promonocytic leukemias.Evi-5, a common site of retroviral integration in AKXD T-cell lymphomas, maps near Gfi-1 on mouse chromosome 5.Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas.Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice.The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11Increased lymphomagenicity and restored disease specificity of AML1 site (core) mutant SL3-3 murine leukemia virus by a second-site enhancer variant evolved in vivo.Retroviral insertions in the VISION database identify molecular pathways in mouse lymphoid leukemia and lymphomaTumorigenesis in transgenic mice: identification and characterization of synergizing oncogenes.Genetically engineered mouse models in cancer researchThe feline leukemia virus long terminal repeat contains a potent genetic determinant of T-cell lymphomagenicityPropylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysisAnalysis of integrated ground squirrel hepatitis virus and flanking host DNA in two hepatocellular carcinomas.Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas.A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.Long-range mapping of Mis-2, a common provirus integration site identified in murine leukemia virus-induced thymomas and located 160 kilobase pairs downstream of Myb.Reducing the genotoxic potential of retroviral vectors.Susceptibility of AKXD recombinant inbred mouse strains to lymphomas.Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.Evidence for long-range oncogene activation by hepadnavirus insertionMoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene.Identification of candidate cancer-causing genes in mouse brain tumors by retroviral taggingProviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.Importance of receptor usage, Fli1 activation, and mouse strain for the stem cell specificity of 10A1 murine leukemia virus leukemogenicity.Long terminal repeat enhancer core sequences in proviruses adjacent to c-myc in T-cell lymphomas induced by a murine retrovirus.Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II.Self-deleting retrovirus vectors for gene therapy.The HNF1/HNF4-dependent We2 element of woodchuck hepatitis virus controls viral replication and can activate the N-myc2 promoter.
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Tumorigenesis by slow-transforming retroviruses--an update.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Tumorigenesis by slow-transforming retroviruses--an update.
@en
type
label
Tumorigenesis by slow-transforming retroviruses--an update.
@en
prefLabel
Tumorigenesis by slow-transforming retroviruses--an update.
@en
P1476
Tumorigenesis by slow-transforming retroviruses--an update.
@en
P2093
M van Lohuizen
P304
P356
10.1016/0304-419X(90)90005-L
P407
P577
1990-12-01T00:00:00Z