Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
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1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an EnigmaSphingolipid signaling in metabolic disordersElevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegenerationThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Molecular evolution of the enzymes involved in the sphingolipid metabolism of Leishmania: selection pressure in relation to functional divergence and conservation.Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels.Harnessing the power of yeast to elucidate the role of sphingolipids in metabolic and signaling processes pertinent to psychiatric disorders.Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.L-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation.Topological and functional characterization of the ssSPTs, small activating subunits of serine palmitoyltransferasePhosphorylation of serine palmitoyltransferase long chain-1 (SPTLC1) on tyrosine 164 inhibits its activity and promotes cell survival.Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cellsSphingolipids and lifespan regulation.Sphingolipids and mitochondrial function, lessons learned from yeastSphingolipid homeostasis in the endoplasmic reticulum and beyond.Sphingolipids and mitochondrial function in budding yeast.Bacterial membrane lipids: diversity in structures and pathways.Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis.Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis.Substrate reduction therapy for Krabbe's disease.CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches.Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites.ORMDL proteins regulate ceramide levels during sterile inflammation.The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutationsHighly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer.The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis.Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis.Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury.Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity.
P2860
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P2860
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
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type
label
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
@en
prefLabel
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
@en
P2860
P356
P1476
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
@en
P2093
Jonathan Lowther
Teresa M Dunn
P2860
P304
P356
10.1042/BST20110769
P577
2012-06-01T00:00:00Z