Fibroblast growth factor homologous factors in the heart: a potential locus for cardiac arrhythmias.
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The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3).FGF13 modulates the gating properties of the cardiac sodium channel Nav1.5 in an isoform-specific manner.Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.Allosteric regulators selectively prevent Ca-feedback of Ca and Na channels
P2860
Fibroblast growth factor homologous factors in the heart: a potential locus for cardiac arrhythmias.
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Fibroblast growth factor homol ...... locus for cardiac arrhythmias.
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label
Fibroblast growth factor homol ...... locus for cardiac arrhythmias.
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prefLabel
Fibroblast growth factor homol ...... locus for cardiac arrhythmias.
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P2860
P1476
Fibroblast growth factor homol ...... locus for cardiac arrhythmias.
@en
P2093
Adam S Barnett
Jessica A Hennessey
P2860
P304
P356
10.1016/J.TCM.2012.05.010
P577
2011-10-01T00:00:00Z