Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease.

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Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease.

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Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease.

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Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease.

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Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease.

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P1476

Possible involvement of the relationship of LRRK2 and autophagy in Parkinson's disease

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P2093

Elisa Pizarro-Estrella

http://www.w3.org/2001/XMLSchema#string

P2860

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro

The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

P304

1129-1133

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P31

scholarly article

P356

10.1042/BST20120095

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mireia Niso-Santano

José M. Fuentes

Rubén Gómez-Sánchez

José Manuel Bravo-San Pedro

Rosa-Ana González Polo

P577

2012-10-01T00:00:00Z

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P698

22988877

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P921

autophagy