Review: microglia of the aged brain: primed to be activated and resistant to regulation.
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Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?Glial Modulation by N-acylethanolamides in Brain Injury and NeurodegenerationMicroglia-Induced Maladaptive Plasticity Can Be Modulated by Neuropeptides In VivoImmune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticityLifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidenceFrom development to dysfunction: microglia and the complement cascade in CNS homeostasisMicroglial pathologyRedox control of microglial function: molecular mechanisms and functional significanceMicroglia recapitulate a hematopoietic master regulator network in the aging human frontal cortexMicroglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative diseaseNeuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle AgePyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats.Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's DiseaseMicroglial Function across the Spectrum of Age and GenderMicroglia: Dynamic Mediators of Synapse Development and Plasticity.Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation.Kinetic modeling without accounting for the vascular component impairs the quantification of [(11)C]PBR28 brain PET dataTranscriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord.Immune involvement in the pathogenesis of schizophrenia: a meta-analysis on postmortem brain studies.Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.Microglia change from a reactive to an age-like phenotype with the time in cultureEffects of long‑term post‑ischemic treadmill exercise on gliosis in the aged gerbil hippocampus induced by transient cerebral ischemia.Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.TGFβ produced by IL-10 redirected astrocytes attenuates microglial activation16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem BrainMicroglial phenotype and adaptation.Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients.Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury.Patterns of Microglial Cell Activation in Alzheimer Disease and Frontotemporal Lobar Degeneration.Reactive retinal microglia, neuronal survival, and the formation of retinal folds and detachments.Functional neural-bone marrow pathways: implications in hypertension and cardiovascular disease.Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activationMicroglia in action: how aging and injury can change the brain's guardians.Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia.RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cellsDual RNA sequencing reveals the expression of unique transcriptomic signatures in lipopolysaccharide-induced BV-2 microglial cells.Microglial and macrophage polarization—new prospects for brain repairPost-mortem analysis of neuroinflammatory changes in human Alzheimer's disease.
P2860
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P2860
Review: microglia of the aged brain: primed to be activated and resistant to regulation.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Review: microglia of the aged brain: primed to be activated and resistant to regulation.
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type
label
Review: microglia of the aged brain: primed to be activated and resistant to regulation.
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prefLabel
Review: microglia of the aged brain: primed to be activated and resistant to regulation.
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P2860
P1476
Review: microglia of the aged brain: primed to be activated and resistant to regulation.
@en
P2093
D M Norden
J P Godbout
P2860
P356
10.1111/J.1365-2990.2012.01306.X
P577
2013-02-01T00:00:00Z