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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionPredicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsBypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia TherapyThe role of drug transporters in the kidney: lessons from tenofovirMind the gap-deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites--a position paper focusing on carotenoids and polyphenolsUnderstanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdlesA population pharmacokinetic approach to describe cephalexin disposition in adult and aged dogsTissue distribution of naringenin conjugated metabolites following repeated dosing of naringin to rats.Few Drugs Display Flip-Flop Pharmacokinetics and These Are Primarily Associated with Classes 3 and 4 of the BDDCSImproved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion techniqueThe biopharmaceutical classification system of excipients.A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cellsHIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications for Antiretroviral Drug DispositionClinical pharmacokinetics of antiretroviral drugs in older persons.Orally active-targeted drug delivery systems for proteins and peptides.Zebrafish as a systems toxicology model for developmental neurotoxicity testing.Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro.Tenapanor administration and the activity of the H+ -coupled transporter PepT1 in healthy volunteers.Clinical determinants of calcineurin inhibitor disposition: a mechanistic review.Uric acid transporters hiding in the intestine.Chemically modified peptides and proteins - critical considerations for oral delivery.Mechanisms involved in the transport of mercuric ions in target tissues.Transporter effects on cell permeability in drug delivery.Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.Gastrointestinal interactions, absorption, splanchnic metabolism and pharmacokinetics of orally ingested phenolic compounds.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Role of ABC transporters in trans-epithelial transport of vitamin K antagonists.Amino Acid Carbamates As Prodrugs Of Resveratrol.Prosecretory effect of loperamide in ileal and colonic mucosae of mice displaying high or low swim stress-induced analgesia associated with high and low endogenous opioid system activity.Piperine-mediated drug interactions and formulation strategy for piperine: recent advances and future perspectives.The intestinal absorption properties of flavonoids in Hippophaë rhamnoides extracts by an in situ single-pass intestinal perfusion model.Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine.Clinical pharmacokinetics of oral drugs in the treatment of multiple myeloma.Development and optimisation of mucoadhesive nanoparticles of acyclovir using design of experiments approach.Predicting tuberculosis treatment outcome using metabolomics.Mango-bagasse functional-confectionery: vehicle for enhancing bioaccessibility and permeability of phenolic compounds.Design of PEG-grafted-PLA nanoparticles as oral permeability enhancer for P-gp substrate drug model Famotidine.Esterification of Quercetin Increases Its Transport Across Human Caco-2 Cells.Influence of verapamil on the pharmacokinetics of oxcarbazepine and of the enantiomers of its 10-hydroxy metabolite in healthy volunteers.Glucuronidation: driving factors and their impact on glucuronide disposition
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Intestinal drug transporters: an overview.
@en
type
label
Intestinal drug transporters: an overview.
@en
prefLabel
Intestinal drug transporters: an overview.
@en
P1476
Intestinal drug transporters: an overview.
@en
P2093
Leslie Z Benet
Margarida Estudante
P304
P356
10.1016/J.ADDR.2012.09.042
P407
P577
2012-10-04T00:00:00Z