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The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesCytotoxic and DNA-targeted therapy in urothelial cancer: have we squeezed the lemon enough?Histone H3.3 maintains genome integrity during mammalian developmentThe tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progressionComprehensive molecular characterization of urothelial bladder carcinomaPlumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cellsAlisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cellsPro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling patEvaluation of toxicogenomics approaches for assessing the risk of nongenotoxic carcinogenicity in rat liverExpression and Therapeutic Potential of SOX9 in Chordoma.p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine.Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis.Detection of expressional changes induced by intrauterine growth restriction in the developing rat mammary gland via exploratory pathways analysis.Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis.Protein mislocalization: mechanisms, functions and clinical applications in cancer.Exploiting tumor cell senescence in anticancer therapyOverexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathwayPathogenetic mechanisms in gastric cancer.Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3.XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cellsInhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollutionPlumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.Association of TBX2 and P21 expression with clinicopathological features and survival of laryngeal squamous cell carcinoma.Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stromaNeural stem and progenitor cell fate transition requires regulation of Musashi1 function.CDKN1A and FANCD2 are potential oncotargets in Burkitt lymphoma and multiple myelomaHuman papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrestMicroRNA-93 promotes ovarian granulosa cells proliferation through targeting CDKN1A in polycystic ovarian syndrome.lncRNA GAS5 enhances G1 cell cycle arrest via binding to YBX1 to regulate p21 expression in stomach cancer.Loss of p21Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibitionNegative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.MAF1 represses CDKN1A through a Pol III-dependent mechanismClinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in bladder cancer.Comparison of Genetic Variants in Cancer-Related Genes between Chinese Hui and Han Populations.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
p21WAF1 and tumourigenesis: 20 years after.
@en
type
label
p21WAF1 and tumourigenesis: 20 years after.
@en
prefLabel
p21WAF1 and tumourigenesis: 20 years after.
@en
P1476
p21WAF1 and tumourigenesis: 20 years after.
@en
P2093
Noel A Warfel
Wafik S El-Deiry
P356
10.1097/CCO.0B013E32835B639E
P577
2013-01-01T00:00:00Z