N-methylation of peptides and proteins: an important element for modulating biological functions.
about
Automated solid-phase peptide synthesis to obtain therapeutic peptidesProtein-like Tertiary Folding Behavior from Heterogeneous BackbonesPhakellistatins: An Underwater Unsolved Puzzle.New p32/gC1qR Ligands for Targeted Tumor Drug Delivery.Comparison of backbone modification in protein β-sheets by α→γ residue replacement and α-residue methylation.Total synthesis and biological evaluation of the antibiotic lysocin E and its enantiomeric, epimeric, and N-demethylated analogues.Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activityTargeting the cyclin-binding groove site to inhibit the catalytic activity of CDK2/cyclin A complex using p27(KIP1)-derived peptidomimetic inhibitorscis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors.Bioactive Peptide of Marine Origin for the Prevention and Treatment of Non-Communicable DiseasesNonribosomal Peptide Synthesis-Principles and Prospects.Synthesis, SAR and biological studies of sugar amino acid-based almiramide analogues: N-methylation leads the way.Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products.N-Methylation as a Strategy for Enhancing the Affinity and Selectivity of RNA-binding Peptides: Application to the HIV-1 Frameshift-Stimulating RNA.Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution.Effect of ester to amide or N-methylamide substitution on bacterial membrane depolarization and antibacterial activity of novel cyclic lipopeptidesTumor Targeting via Integrin Ligands.Integrin modulators: a patent review.Review backbone N-modified peptides: How to meet the challenge of secondary amine acylation.Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.Novel approaches to the design of bioavailable melanotropins.Toward accurately modeling N-methylated cyclic peptides.Stable Peptides Instead of Stapled Peptides: Highly Potent αvβ6-Selective Integrin Ligands.αvβ3- or α5β1-Integrin-Selective Peptidomimetics for Surface Coating.Progress with peptide scanning to study structure-activity relationships: the implications for drug discovery.Peptide N-Amination Supports β-Sheet Conformations.Peptidomimetic therapeutics: scientific approaches and opportunities.Macrocycles: lessons from the distant past, recent developments, and future directions.N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: application to Sansalvamide A peptide analogs.Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity.HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells.Discovery of cyclosporine A and its analogs as broad-spectrum anti-influenza drugs with a high in vitro genetic barrier of drug resistanceMetadynamics Simulations Rationalise the Conformational Effects Induced by N-Methylation of RGD Cyclic Hexapeptides.Interface Immobilization Chemistry of cRGD-based Peptides Regulates Integrin Mediated Cell Adhesion.Exploring the Role of RGD-Recognizing Integrins in Cancer.Histone Methylation by Temozolomide; A Classic DNA Methylating Anticancer Drug.DMAP-assisted sulfonylation as an efficient step for the methylation of primary amine motifs on solid support.Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing.Residue-Specific Peptide Modification: A Chemist's Guide.
P2860
Q27001623-7FEB2FA6-4671-45C5-A064-4C396FE623AEQ27679538-55C6EC51-9D43-44DF-95A4-4A65CA302F47Q33365075-3B721AFE-A109-4125-9E01-689027C6C37DQ33694228-A46882B1-E155-49C3-8AC2-354CA98B86D1Q34030914-D29C9F37-DBA5-4016-B71C-978C869FA2B9Q34667080-5715FDF9-E9AE-49C7-8B94-B98D4729B6E3Q35100606-11F07EB8-BDAE-4117-B719-E8149FBE3FF2Q35542088-C4F3E4F6-4D14-4E56-B198-54B637B4447CQ35764128-1C410070-C93F-4F56-8963-95A06E6B979FQ36128120-45E7E4C9-3168-439F-ADC8-4DFA81025441Q36304654-265B0A69-0355-4AE9-AE7E-6CB2EB7E5E83Q36316177-B05482A8-8D87-4CA9-A535-F7CDC2FD4DB9Q36331518-3B3E2616-DC5E-4ED7-AB2C-89177DDBEBB9Q36392711-F235161C-D9D2-47AB-A5C1-9213B630BC4FQ36482677-7497B0ED-36B9-41A1-85DB-AB9A345C7C3FQ36488030-36FF69D7-12B7-4C6F-BC42-0BC706648A8CQ37209021-7BE680EE-42E9-46D0-8484-02233250EB50Q38134759-D5ACD691-B3F4-4E8D-ACE1-8B242498B1E7Q38139612-C0F3E5B3-6A4C-4422-B33C-DB6FBE6621AFQ38533393-863E59DE-DA76-4038-BF00-654F42CB73B7Q38539666-6647E9E0-28C2-4318-8A91-63357D6F1692Q38658728-C737F0BD-AA99-4ED3-9FB4-9A458E0ADEDFQ38762282-617034ED-3477-4866-93DC-4F126E4EC0CBQ38811936-C09098E9-A661-4AB2-9C21-ECB295E7C087Q38852942-2E268075-F863-43FF-8A12-852E7D6685A4Q38867099-A0B5B947-B24B-4A72-93FF-F01B7D6EDB41Q39010481-C904ACF8-F14A-4C47-8483-655023B7C0D4Q39011193-B979C276-A897-496E-956D-757F0484A8D7Q39065925-BFB2E029-3EC1-44E8-9632-BD722B178B65Q39141534-A3028DC3-ECDE-4F62-AF7E-C1A4D1B9CC1BQ39292881-332A390A-7807-48D1-90FA-EF9D4B4BB5F4Q40225647-15060E3E-CB16-4763-B3E7-1EC9FBCABF82Q40593477-54B4302F-1DF9-4B27-8E00-A07A026D6D5CQ40653425-8F87A7E9-0511-4F49-AD54-0339036A4C60Q41157466-A3E0F7CF-6F34-430A-A22E-CAC798CBACBFQ41670915-6B2CE23C-D41A-4F36-8695-3BBE845BA04CQ42108435-3EFA7BDA-CCB2-438A-A392-E287E95D954FQ42264007-67C13A68-CC41-4A98-B172-6B0A2E2C5ADBQ42287023-22372E08-F65C-4262-8A35-F0C4F08B92D1Q43905157-60F1896D-98BD-465E-8D16-890CA6F45505
P2860
N-methylation of peptides and proteins: an important element for modulating biological functions.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
N-methylation of peptides and ...... dulating biological functions.
@en
type
label
N-methylation of peptides and ...... dulating biological functions.
@en
prefLabel
N-methylation of peptides and ...... dulating biological functions.
@en
P2093
P2860
P356
P1476
N-methylation of peptides and ...... dulating biological functions.
@en
P2093
Florian Rechenmacher
Horst Kessler
Jayanta Chatterjee
P2860
P304
P356
10.1002/ANIE.201205674
P407
P577
2012-11-19T00:00:00Z