Hitting the golden TORget: curcumin's effects on mTOR signaling. - Wikidata - wikimedia - TriplyDB

Hitting the golden TORget: curcumin's effects on mTOR signaling.

Hitting the golden TORget: curcumin's effects on mTOR signaling.

http://www.wikidata.org/entity/Q38070194

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HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells.Natural products as potential cancer therapy enhancers: A preclinical update.Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling Curcumin inhibits cell growth and invasion and induces apoptosis through down-regulation of Skp2 in pancreatic cancer cells Natural compounds to overcome cancer chemoresistance: toxicological and clinical issues.Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?Anti-Apoptotic Effects of Osteopontin via the Up-Regulation of AKT/mTOR/β-Catenin Loop in Acute Myeloid Leukemia Cells.Analysis of the anticancer activity of curcuminoids, thiotryptophan and 4-phenoxyphenol derivatives.Inhibition of PI3K/Akt/mTOR signaling by natural products.Curcumin inhibits cell proliferation and motility via suppression of TROP2 in bladder cancer cells.

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P2860

Hitting the golden TORget: curcumin's effects on mTOR signaling.

http://www.wikidata.org/entity/Q38070194

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artikel ilmiah

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artículo científico

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name

Hitting the golden TORget: curcumin's effects on mTOR signaling.

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type

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Hitting the golden TORget: curcumin's effects on mTOR signaling.

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Hitting the golden TORget: curcumin's effects on mTOR signaling.

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1871520611313070004

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Anti-Cancer Agents in Medicinal Chemistry

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Hitting the golden TORget: curcumin's effects on mTOR signaling.

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Christopher S Beevers

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Hongyu Zhou

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P2860

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Identification of Protor as a novel Rictor-binding component of mTOR complex-2

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

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988-994

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scholarly article

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10.2174/1871520611313070004

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