Phenylalanine hydroxylase: function, structure, and regulation. - Wikidata - wikimedia - TriplyDB

Phenylalanine hydroxylase: function, structure, and regulation.

Phenylalanine hydroxylase: function, structure, and regulation.

http://www.wikidata.org/entity/Q38086186

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Advances in the nutritional and pharmacological management of phenylketonuria Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogenLegionella pneumophila Structural insights into the regulation of aromatic amino acid hydroxylation Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease X-ray Scattering Studies of Protein Structural Dynamics.Protein homeostasis disorders of key enzymes of amino acids metabolism: mutation-induced protein kinetic destabilization and new therapeutic strategies.Amino Acid Medical Foods Provide a High Dietary Acid Load and Increase Urinary Excretion of Renal Net Acid, Calcium, and Magnesium Compared with Glycomacropeptide Medical Foods in Phenylketonuria.A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis.Characterization of phenylalanine hydroxylase gene mutations in phenylketonuria in Xinjiang of China.The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers.Accurate prediction of functional effects for variants by combining gradient tree boosting with optimal neighborhood properties.First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase.Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.The structural origin of metabolic quantitative diversity.Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis.Tyrosine and tryptophan hydroxylases as therapeutic targets in human disease.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Characterization of Multi-subunit Protein Complexes of Human MxA Using Non-denaturing Polyacrylamide Gel-electrophoresis.Recovery of pan-genotypic and genotype-specific amino acid alterations in chronic hepatitis C after viral clearance: transition at the crossroad of metabolism and immunity.Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring.Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in Dopa-responsive dystonia.Glycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial.Molecular Genetic Analysis of the Variable Number of Tandem-Repeat Alleles at the Phenylalanine Hydroxylase Gene in Iranian Azeri Turkish Population.Phenylketonuria: A new look at an old topic, advances in laboratory diagnosis, and therapeutic strategies.Metabolomic Insights into the Nutritional Status of Adults and Adolescents with Phenylketonuria Consuming a Low-Phenylalanine Diet in Combination with Amino Acid and Glycomacropeptide Medical Foods.Metabolomic changes demonstrate reduced bioavailability of tyrosine and altered metabolism of tryptophan via the kynurenine pathway with ingestion of medical foods in phenylketonuria.NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application.Phenylalanine iminoboronates as new phenylalanine hydroxylase modulators Common and differential transcriptional responses to different models of traumatic stress exposure in rats

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Phenylalanine hydroxylase: function, structure, and regulation.

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Phenylalanine hydroxylase: function, structure, and regulation.

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Phenylalanine hydroxylase: function, structure, and regulation.

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Phenylalanine hydroxylase: function, structure, and regulation

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Aurora Martinez

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Marte I Flydal

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P2860

Evidence for a high-spin Fe(IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylase

Direct evidence for a phenylalanine site in the regulatory domain of phenylalanine hydroxylase

Structural basis of autoregulation of phenylalanine hydroxylase

Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates

Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation

Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability

Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

Missense mutations in the N-terminal domain of human phenylalanine hydroxylase interfere with binding of regulatory phenylalanine

FolX and FolM are essential for tetrahydromonapterin synthesis in Escherichia coli and Pseudomonas aeruginosa

Involvement of the global Crp regulator in cyclic AMP-dependent utilization of aromatic amino acids by Pseudomonas putida.

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341-349

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scholarly article

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10.1002/IUB.1150

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4

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Aurora Martinez

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2013-03-04T00:00:00Z

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23457044

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