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The multifaceted roles of the HORMA domain in cellular signalingDNA repair diseases: What do they tell us about cancer and aging?Hypermutation in human cancer genomes: footprints and mechanismsA novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiaeSequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.DNA damage related crosstalk between the nucleus and mitochondria.Chromatin Regulates Genome Targeting with Cisplatin.Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma.A dnaN plasmid shuffle strain for rapid in vivo analysis of mutant Escherichia coli β clamps provides insight into the role of clamp in umuDC-mediated cold sensitivity.Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.Clusters of Multiple Mutations: Incidence and Molecular MechanismsDNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cellsThe choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis.Replicating damaged DNA in eukaryotes.Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms.Mechanisms of Post-Replication DNA RepairMechanisms of base substitution mutagenesis in cancer genomes.The Fanconi anemia ID2 complex: dueling saxes at the crossroads.The essential kinase ATR: ensuring faithful duplication of a challenging genome.DNA replication stress and cancer: cause or cure?Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells.Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides.In vivo evidence for translesion synthesis by the replicative DNA polymerase δ.Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.Histone H3.3 is required to maintain replication fork progression after UV damage.The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.The Cartography of UV-induced DNA Damage Formation and DNA Repair.Coordination of DNA single strand break repair.Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.Translesion DNA polymerases in eukaryotes: what makes them tick?Mechanisms of DNA damage, repair, and mutagenesis.Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen.Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.Y-family DNA polymerase-independent gap-filling translesion synthesis across aristolochic acid-derived adenine adducts in mouse cells.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Translesion DNA synthesis and mutagenesis in eukaryotes
@en
type
label
Translesion DNA synthesis and mutagenesis in eukaryotes
@en
prefLabel
Translesion DNA synthesis and mutagenesis in eukaryotes
@en
P2860
P1476
Translesion DNA synthesis and mutagenesis in eukaryotes
@en
P2093
Julian E Sale
P2860
P304
P356
10.1101/CSHPERSPECT.A012708
P577
2013-03-01T00:00:00Z