Hedgehog signaling pathway and cancer therapeutics: progress to date.
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Tamoxifen Resistance: Emerging Molecular TargetsPilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma.Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factorsEstablishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tractVismodegib: First-in-Class Hedgehog Pathway Inhibitor for Metastatic or Locally Advanced Basal Cell Carcinoma.Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse modelOsteosarcoma With Apparent Ewing Sarcoma Gene Rearrangement.Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment.Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives.GLI2 expression levels in radical nephrectomy specimens as a predictor of disease progression in patients with metastatic clear cell renal cell carcinoma following treatment with sunitinib.Cryptolepine derivative-6h inhibits liver fibrosis in TGF-β1-induced HSC-T6 cells by targeting the Shh pathway.Protein arginine methyltransferase 1 promoted the growth and migration of cancer cells in esophageal squamous cell carcinoma.Association of Itraconazole, a Hedgehog Inhibitor, and Bladder Cancer.Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications.Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets.The long noncoding RNA TUG1 acts as a competing endogenous RNA to regulate the Hedgehog pathway by targeting miR-132 in hepatocellular carcinoma.Strategies to target the Hedgehog signaling pathway for cancer therapy.The Stromal Niche for Epithelial Stem Cells: A Template for Regeneration and a Brake on Malignancy.Sonic hedgehog signaling pathway mediates development of hepatocellular carcinoma.Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth
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Hedgehog signaling pathway and cancer therapeutics: progress to date.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Hedgehog signaling pathway and cancer therapeutics: progress to date.
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type
label
Hedgehog signaling pathway and cancer therapeutics: progress to date.
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prefLabel
Hedgehog signaling pathway and cancer therapeutics: progress to date.
@en
P2860
P1433
P1476
Hedgehog signaling pathway and cancer therapeutics: progress to date.
@en
P2093
Edward J Kim
Joshua M Ruch
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P2888
P304
P356
10.1007/S40265-013-0045-Z
P577
2013-05-01T00:00:00Z
P6179
1041266987