The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease.
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Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolitesSmaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes.The ACMSD gene, involved in tryptophan metabolism, is mutated in a family with cortical myoclonus, epilepsy, and parkinsonism.A Novel p.Glu298Lys Mutation in the ACMSD Gene in Sporadic Parkinson's Disease.Kynurenine Monooxygenase (KMO) Inhibitors for the Treatment of Acute Pancreatitis and Neurodegenerative Disorders.Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress.Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.Mood symptoms correlate with kynurenine pathway metabolites following sports-related concussion.Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging
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The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease.
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article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
@sq
artículo científico
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name
The causative role and therape ...... in neurodegenerative disease.
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type
label
The causative role and therape ...... in neurodegenerative disease.
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prefLabel
The causative role and therape ...... in neurodegenerative disease.
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P2860
P1476
The causative role and therape ...... y in neurodegenerative disease
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P2093
Flaviano Giorgini
Nigel S Scrutton
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P2888
P304
P356
10.1007/S00109-013-1046-9
P577
2013-05-01T00:00:00Z
P6179
1030176240