DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.
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DNA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of RadioresistanceNovel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationRole of Natural Radiosensitizers and Cancer Cell Radioresistance: An UpdateTherapeutic Implications for Overcoming Radiation Resistance in Cancer TherapyChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingDNA studies using atomic force microscopy: capabilities for measurement of short DNA fragmentsTargeting nucleophosmin 1 represents a rational strategy for radiation sensitization.A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repairDrugging the Cancers Addicted to DNA Repair.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells.Acquisition of radioresistance in docetaxel-resistant human lung adenocarcinoma cells is linked with dysregulation of miR-451/c-Myc-survivin/rad-51 signaling.Radioimmunotherapy with α-particle-emitting radionuclides.The DNA2 nuclease/helicase is an estrogen-dependent gene mutated in breast and ovarian cancersIn vitro assessment of antibody-conjugated gold nanorods for systemic injections.Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.DNA end resection is needed for the repair of complex lesions in G1-phase human cells.The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells.Mechanistic Modeling of Dose and Dose Rate Dependences of Radiation-Induced DNA Double Strand Break Rejoining Kinetics in Saccharomyces cerevisiae.BRCA1 Mutation: A Predictive Marker for Radiation Therapy?Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.Mechanistic Modelling and Bayesian Inference Elucidates the Variable Dynamics of Double-Strand Break Repair.Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitizationA new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy.Ionizing radiation-induced DNA injury and damage detection in patients with breast cancerMEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress.Biology of high single doses of IORT: RBE, 5 R's, and other biological aspectsCharacterization of in vitro radiosensitization in mammalian cells using biomathematical modelling: implications for hypofractionated radiotherapy with a combined modality approachKub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.microRNAs in cancer cell response to ionizing radiation.Increasing the α 2, 6 sialylation of glycoproteins may contribute to metastatic spread and therapeutic resistance in colorectal cancer.Radiation oncology in vitro: trends to improve radiotherapy through molecular targets.Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways.Modeling DNA damage-induced pneumopathy in mice: insight from danger signaling cascades.Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells.TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation.Purine 5',8-cyclo-2'-deoxynucleoside lesions: formation by radical stress and repair in human breast epithelial cancer cells.
P2860
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P2860
DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
DNA double-strand break repair ...... d target in radiation therapy.
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type
label
DNA double-strand break repair ...... d target in radiation therapy.
@en
prefLabel
DNA double-strand break repair ...... d target in radiation therapy.
@en
P2093
P2860
P356
P1476
DNA double-strand break repair ...... d target in radiation therapy.
@en
P2093
Aashish Soni
Emil Mladenov
George Iliakis
Simon Magin
P2860
P356
10.3389/FONC.2013.00113
P577
2013-05-10T00:00:00Z