Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid. - Wikidata - wikimedia - TriplyDB

Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid.

Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid.

http://www.wikidata.org/entity/Q38113683

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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease Molecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation Neural Plasticity in Multiple Sclerosis: The Functional and Molecular Background Clearance systems in the brain-implications for Alzheimer disease Advances in Alzheimer's disease drug development Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease.Tau accumulation in the nucleus accumbens in tangle-predominant dementia Smoking and increased Alzheimer's disease risk: a review of potential mechanisms No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis.Are cases with tau pathology occurring in the absence of Aβ deposits part of the AD-related pathological process?Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease Endpoints for Pre-Dementia AD Trials: A Report from the EU/US/CTAD Task Force.Florbetapir positron emission tomography and cerebrospinal fluid biomarkers.Cerebrospinal Fluid Biomarkers for the Differential Diagnosis between Alzheimer's Disease and Frontotemporal Lobar Degeneration: Systematic Review, HSROC Analysis, and Confounding Factors.Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer's Disease Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study.Longitudinal cerebrospinal fluid biomarker measurements in preclinical sporadic Alzheimer's disease: A prospective 9-year study Alzheimer's disease biomarkers: walk with deliberate haste, don't run blithely on?Tau passive immunization inhibits not only tau but also Aβ pathology Patterns of Cortical and Subcortical Amyloid Burden across Stages of Preclinical Alzheimer's Disease.Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.Invited review: Drug development for tauopathies.Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases."Boomerang Neuropathology" of Late-Onset Alzheimer's Disease is Shrouded in Harmful "BDDS": Breathing, Diet, Drinking, and Sleep During Aging.Yeast Model of Amyloid-β and Tau Aggregation in Alzheimer's Disease.Rethinking on the concept of biomarkers in preclinical Alzheimer's disease.Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143-Further Implications for Alzheimer's Therapy Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau.Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients.The past, present, and future of disease-modifying therapies for Alzheimer's disease.Intracranial Arterial 4D Flow in Individuals with Mild Cognitive Impairment is Associated with Cognitive Performance and Amyloid Positivity.Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice.Structural Connectivity Alterations Along the Alzheimer's Disease Continuum: Reproducibility Across Two Independent Samples and Correlation with Cerebrospinal Fluid Amyloid-β and Tau.Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies.Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections.The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease.Word-list intrusion errors predict progression to mild cognitive impairment.Amyloid-β may be released from non-junctional varicosities of axons generated from abnormal tau-containing brainstem nuclei in sporadic Alzheimer's disease: a hypothesis.

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Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid.

http://www.wikidata.org/entity/Q38113683

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Intraneuronal tau aggregation ...... of tau in cerebrospinal fluid.

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Intraneuronal tau aggregation ...... of tau in cerebrospinal fluid.

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Intraneuronal tau aggregation ...... of tau in cerebrospinal fluid.

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Acta Neuropathologica

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Intraneuronal tau aggregation ...... of tau in cerebrospinal fluid.

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Heiko Braak

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Kelly Del Tredici

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P2860

Where, when, and in what form does sporadic Alzheimerʼs disease begin?

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Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Pathways towards and away from Alzheimer's disease

Neuropathological stageing of Alzheimer-related changes

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

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s00401-013-1139-0

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631-641

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10.1007/S00401-013-1139-0

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5

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126

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Henrik Zetterberg

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2013-06-12T00:00:00Z

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237147165

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cerebrospinal fluid