Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease - Wikidata - wikimedia - TriplyDB

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

http://www.wikidata.org/entity/Q28242505

about

Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death Rapid neurofibrillary tangle formation after localized gene transfer of mutated tau Identification of septins in neurofibrillary tangles in Alzheimer's disease Possible involvement of copper(II) in Alzheimer disease.Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem The role of tau in neurodegenerative diseases and its potential as a therapeutic target Tau physiology and pathomechanisms in frontotemporal lobar degeneration Tau Structures Melanopsin retinal ganglion cell loss and circadian dysfunction in Alzheimer's disease (Review)The preclinical phase of the pathological process underlying sporadic Alzheimer's disease Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype Phosphorylation by neuronal cdc2-like protein kinase promotes dimerization of Tau protein in vitro Argyrophilic grain disease Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease Olfactory ERPs in an odor/visual congruency task differentiate ApoE ε4 carriers from non-carriers Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers Alzheimer disease models and human neuropathology: similarities and differences O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro.Expression in cultured human neuroblastoma cells of epitopes associated with affected neurons in Alzheimer's disease.Casein kinase II alteration precedes tau accumulation in tangle formation Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.ATP-induced loss of Alz-50 immunoreactivity with the A68 proteins from Alzheimer brain is mediated by ubiquitin.REVIEW: tau protein pathology in Alzheimer's disease and related disorders.Identification of oligomers at early stages of tau aggregation in Alzheimer's disease.Tau pathology generated by overexpression of tau.Mechanisms of tau-induced neurodegeneration.Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration Structure and pathology of tau protein in Alzheimer disease.Hypothesis: microtubules, a key to Alzheimer disease Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons.

P2860

Q24563378-CD20DA4C-9B4C-4010-BB20-4CFB2E22E9A5 Q24599152-9154284E-6330-4430-8876-1CEB5BEC9AD8 Q24606199-A94AA78A-2F8D-4B27-8408-26008E8EC8EE Q24675907-9E1C2B86-47C8-4CEC-915F-58B545BB2497 Q24681982-7033A848-D128-430A-8535-52DE9A4783F7 Q24812673-81CB5C00-8A3C-492F-8466-3CDAC545704A Q26739412-AF0BAF5D-20E4-4116-8085-BD2C64EDC538 Q26768648-E21B894D-8058-4F03-A66A-2DA08D3C9EEA Q26769957-D2DBEA57-FF94-441C-943E-08750F94F2D6 Q27004724-9AAF03FE-424B-4CF6-BFB7-2E09C2E4D1AA Q27005032-AD885CBE-E2C3-4ED8-9BB5-D40531A040D8 Q28070250-3040098B-B3A6-46E7-BAD7-CCEA3C8CA116 Q28076921-ADCF9C57-E8E0-412A-A01E-E096C27013E7 Q28079228-C629DD31-87E5-4867-B4B9-BC8352EAA2AF Q28083428-2AB5E1A6-B249-48FF-8560-360E6C6D8353 Q28200189-13430BCD-05BB-443C-A3BC-EE187A678630 Q28211236-459634E6-6343-4963-B744-6DB620FC2D44 Q28253196-57930984-283A-4F85-9FF2-666E4E8EF805 Q28266563-FBC7BC5F-B4EF-4B0A-BE1B-7CC86A100DFB Q28345670-9EFAE076-2BA9-4DC7-8A95-3C66B1660D77 Q28386238-19FAF66E-E175-4C9E-99E9-DCBB21FAF80A Q28391803-822CD1F0-B143-4BC0-8764-00E11D303F82 Q28397264-0538406D-56BF-4C18-9EC0-D23A36186FFD Q30499574-3BA37872-883B-4E50-91E8-BEECC1940D64 Q30528027-D8569308-CC1F-4DF6-BB6C-6B43904F8199 Q31111749-FE105375-D645-4C1B-B9C1-4AB3AC8BA5AF Q33254317-FA278C69-B27D-4C47-8332-03AC7A8A6EAA Q33280278-A6D26BBC-9A0E-4575-8330-13861AC20FAB Q33300947-2254209D-F095-4B7E-9F75-321AF8114906 Q33359744-B6138D5C-FF77-446B-B917-D077F8A27634 Q33633043-E43DF26D-02F4-4428-821B-45453BCED273 Q33647231-3235A939-B1E3-4604-8E8C-2EE81CB0478D Q33694030-6439D123-39E9-46E1-91B9-AFC7B10E294C Q33713341-76F9DA92-AB80-4EBC-9C7C-3E43A766A538 Q33793293-B1F5E692-6434-4862-83E0-92F24C34FAA9 Q33859830-5C3ABA3B-1C55-41C9-961A-B351FE69A4B6 Q34155383-4A9CC54A-4151-485B-B652-02EAC389B4CF Q34280787-90EACC11-5ECE-42B1-ACE8-CCDC1266D71B Q34314365-605481F5-EB89-40F5-AFD8-1828E7D34E3E Q34340308-FD076220-BFEE-4F34-A806-179453E1ABEF

P2860

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

http://www.wikidata.org/entity/Q28242505

description

1989 nî lūn-bûn

@nan

1989 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

1989 թվականի հունվարին հրատարակված գիտական հոդված

@hy

1989年の論文

@ja

1989年論文

@yue

1989年論文

@zh-hant

1989年論文

@zh-hk

1989年論文

@zh-mo

1989年論文

@zh-tw

1989年论文

@wuu

name

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@ast

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@en

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@nl

type

label

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@ast

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@en

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@nl

prefLabel

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@ast

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@en

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@nl

P1433

Q28242505-D3B5176C-385D-4BC3-8996-941445B93444

P1476

Q28242505-B6FE69B6-6377-49B3-931D-F47E381C75BB

P2093

Q28242505-1163733B-1F5F-4CB6-8B5B-FAC96161B02C

Q28242505-158747F0-8A41-4041-88BA-B06881C6DFE9

Q28242505-4323FACD-5507-4109-93EB-B26D35E13761

Q28242505-4438B763-15CA-4587-A4C2-E78F17767779

Q28242505-6C51FA5D-3649-4207-95F4-0AF5E9636663

Q28242505-B722BE92-600E-479C-8A48-DF0201CE29CE

Q28242505-B7A5A341-C0E4-49F4-99EE-8E7C078056D5

Q28242505-CF2DA24F-78DA-4215-9B2C-E79B04326829

Q28242505-F184D368-FA6F-4AFF-A2F6-2179CD6498B6

P304

Q28242505-9DEFB9B3-B313-4F8E-857E-5EFFB81B25B7

P31

Q28242505-B98EF98C-4E52-4687-8D86-22B024706363

P3181

Q28242505-7C9F5757-9B26-4D0B-9A6D-89796BDE1E6E

P356

Q28242505-892F4D10-026C-47E4-8A8F-CFA719CF080D

P407

Q28242505-F3ED1B55-7424-438A-87FA-411AD8A08F57

P433

Q28242505-40B4D009-96BA-4A89-B71E-41320845C84A

P478

Q28242505-480CAB7B-61CE-43FE-BBE8-E8F71D383AE3

P50

Q28242505-B50D719C-D9A8-4D1C-9A64-4C0D4E3B51BF

P577

Q28242505-05F36B9E-04A9-4634-96F5-8351E554A0DC

P698

Q28242505-D9CD2330-1F5C-4B6D-BA09-3FD1D05516FC

P921

Q28242505-04B7FDFF-82C3-46FD-9058-F3E6F0FC0557

Q28242505-556C769E-1C5F-4B51-AC39-52958AE47FE8

P3181

P356

0006-8993(89)91396-6

P1433

P1476

Accumulation of abnormally pho ...... tangles in Alzheimer's disease

@en

P2093

C Bancher

http://www.w3.org/2001/XMLSchema#string

C Brunner

http://www.w3.org/2001/XMLSchema#string

F Seitelberger

http://www.w3.org/2001/XMLSchema#string

G Wiche

http://www.w3.org/2001/XMLSchema#string

H Budka

http://www.w3.org/2001/XMLSchema#string

H M Wisniewski

http://www.w3.org/2001/XMLSchema#string

I Grundke-Iqbal

http://www.w3.org/2001/XMLSchema#string

K Iqbal

http://www.w3.org/2001/XMLSchema#string

K Jellinger

http://www.w3.org/2001/XMLSchema#string

P304

90-9

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

487385

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/0006-8993(89)91396-6

http://www.w3.org/2001/XMLSchema#string

P407

P433

1-2

http://www.w3.org/2001/XMLSchema#string

P478

477

http://www.w3.org/2001/XMLSchema#string

P50

P577

1989-01-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

2495152

http://www.w3.org/2001/XMLSchema#string

P921

Alzheimer's disease

phosphorylation