Opportunities and hurdles in the treatment of BRCA1-related breast cancer. - Wikidata - wikimedia - TriplyDB

Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

http://www.wikidata.org/entity/Q38129725

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Recommendations for the implementation of BRCA testing in the care and treatment pathways of ovarian cancer patients.Emerging therapeutic targets in metastatic progression: A focus on breast cancer.MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression.Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect.Mutational landscape of the essential autophagy gene BECN1 in human cancers.Sensitive and selective DNA probe based on "turn-on" photoluminescence of C-dots@RGO.Impact of germline and somatic BRCA1/2 mutations: tumor spectrum and detection platforms.PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells.Genomic hallmarks of homologous recombination deficiency in invasive breast carcinomas.Expression of miR-146a-5p in breast cancer and its role in proliferation of breast cancer cells.

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Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

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Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

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Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

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Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

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Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

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J Jonkers

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R Drost

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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

Global cancer statistics

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

Purified human BRCA2 stimulates RAD51-mediated recombination

Roles of BRCA1 in centrosome duplication

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

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3753-3763

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10.1038/ONC.2013.329

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