Preclinical and clinical pharmacokinetic/pharmacodynamic considerations for antibody-drug conjugates.
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Comparative clinical pharmacokinetics of antibody-drug conjugates in first-in-human Phase 1 studiesMaytansine-loaded star-shaped folate-core PLA-TPGS nanoparticles enhancing anticancer activityTherapeutic evaluation of monoclonal antibody-maytansinoid conjugate as a model of RON-targeted drug delivery for pancreatic cancer treatment.Potential of antibody-drug conjugates and novel therapeutics in breast cancer management.Antibody-drug conjugates: a mini-review. The synopsis of two approved medicines.Antibody Drug Conjugates: Application of Quantitative Pharmacology in Modality Design and Target Selection.Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates.Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia.Targeted Therapies Against Growth Factor Signaling in Breast Cancer.From linear 'dogma' and trastuzumab-emtansine to future transcriptional circuitry-based drug discovery for breast cancer.Breast Cancer Immunotherapy.Quantitative translational modeling to facilitate preclinical to clinical efficacy & toxicity translation in oncology.
P2860
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P2860
Preclinical and clinical pharmacokinetic/pharmacodynamic considerations for antibody-drug conjugates.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Preclinical and clinical pharm ...... for antibody-drug conjugates.
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label
Preclinical and clinical pharm ...... for antibody-drug conjugates.
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prefLabel
Preclinical and clinical pharm ...... for antibody-drug conjugates.
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P2093
P2860
P1476
Preclinical and clinical pharm ...... for antibody-drug conjugates.
@en
P2093
Alison Betts
Joseph Boni
Puja Sapra
P2860
P304
P356
10.1586/17512433.2013.827405
P407
P577
2013-08-26T00:00:00Z