Advances in huntington disease drug discovery: novel approaches to model disease phenotypes.
about
Modeling diseases of noncoding unstable repeat expansions using mutant pluripotent stem cells.HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.iPSC-based drug screening for Huntington's disease.Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets.Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington's Disease Neural Stem Cells.Mitochondrial modulators improve lipid composition and attenuate memory deficits in experimental model of Huntington's disease.Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.
P2860
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P2860
Advances in huntington disease drug discovery: novel approaches to model disease phenotypes.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Advances in huntington disease ...... s to model disease phenotypes.
@en
type
label
Advances in huntington disease ...... s to model disease phenotypes.
@en
prefLabel
Advances in huntington disease ...... s to model disease phenotypes.
@en
P2093
P2860
P356
P1476
Advances in huntington disease ...... s to model disease phenotypes.
@en
P2093
Ignacio Munoz-Sanjuan
Jamshid Arjomand
Jonathan Bard
Michael D Wall
Ovadia Lazari
P2860
P304
P356
10.1177/1087057113510320
P577
2013-11-06T00:00:00Z